STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tram-1Translocating chain-associated membrane protein; Belongs to the TRAM family. (373 aa)    
Predicted Functional Partners:
pisy-1
CDP-diacylglycerol--inositol 3-phosphatidyltransferase.
   
  
 0.851
dnj-29
J domain-containing protein.
   
 
 0.836
tmem-107
TMEM (Human TransMEMbrane protein) homolog.
      
 0.803
aman-2
Alpha-mann_mid domain-containing protein.
   
  
 0.741
sec-23
Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily.
   
  
 0.714
aass-1
AminoAdipate-Semialdehyde Synthase homolog.
   
  
 0.704
rpi-2
Protein XRP2; Acts as a GTPase-activating protein (GAP) for tubulin in concert with tubulin-specific chaperone C, but does not enhance tubulin heterodimerization.
      
 0.693
set-14
SET domain-containing protein 14.
      
 0.664
tbc-11
Rab-GAP TBC domain-containing protein.
      
 0.660
poml-1
PON (Paraoxonase) and MEC-6 Like.
      
 0.660
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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