STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
lid-1Abhydrolase domain-containing protein lid-1; Acts coordinately with atgl-1 within the lipolytic cascade to distribute stored energy to tissues during nutritional deprivation. Belongs to the peptidase S33 family. ABHD4/ABHD5 subfamily. (365 aa)    
Predicted Functional Partners:
atgl-1
Patanin-like phospholipase domain-containing protein; Catalyzes the initial step in triglyceride hydrolysis in adipocyte and non-adipocyte lipid droplets (By similarity). May play a role in the response of the organism to starvation, enhancing hydrolysis of triglycerides and providing free fatty acids to other tissues to be oxidized in situations of energy depletion. Acts coordinately with lid-1 within the lipolytic cascade to distribute stored energy to tissues. Together with lipid droplet protein cgi-58, regulates lipid reserves as well as lipid droplet size and localization during t [...]
   
 
 0.933
pks-1
PolyKetide Synthase.
  
 
 0.849
hosl-1
Uncharacterized protein.
    
 0.828
K01A2.5
AB hydrolase-1 domain-containing protein.
      
 0.825
acl-1
Putative 1-acyl-sn-glycerol-3-phosphate acyltransferase acl-1; Converts lysophosphatidic acid (LPA) into phosphatidic acid by incorporating an acyl moiety at the sn-2 position of the glycerol backbone.
   
  
 0.735
dgat-2
Acyl-CoA:DiacylGlycerol AcylTransferase.
   
  
 0.720
acl-2
Putative 1-acyl-sn-glycerol-3-phosphate acyltransferase acl-2; Converts lysophosphatidic acid (LPA) into phosphatidic acid by incorporating an acyl moiety at the sn-2 position of the glycerol backbone.
   
  
 0.714
plin-1
Perilipin-1 homolog; Lipid droplet-associated protein which plays a role in lipid droplet clustering. Belongs to the perilipin family.
   
  
 0.708
F37C12.3
Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.
  
 0.626
Y56A3A.19
Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.
  
 0.626
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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