node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
F33D4.4 | cgt-1 | F33D4.4.1 | T06C12.10.1 | Putative sphingolipid delta(4)-desaturase; Acts as a sphingolipid delta(4)-desaturase; Belongs to the fatty acid desaturase type 1 family. DEGS subfamily. | Ceramide glucosyltransferase 1; Catalyzes the first glycosylation step in glycosphingolipid biosynthesis, the transfer of glucose to ceramide. Belongs to the glycosyltransferase 2 family. | 0.921 |
F33D4.4 | cgt-3 | F33D4.4.1 | F59G1.1b.1 | Putative sphingolipid delta(4)-desaturase; Acts as a sphingolipid delta(4)-desaturase; Belongs to the fatty acid desaturase type 1 family. DEGS subfamily. | Ceramide glucosyltransferase 3; Catalyzes the first glycosylation step in glycosphingolipid biosynthesis, the transfer of glucose to ceramide. Seems to be the major active form in the nematode. | 0.923 |
F33D4.4 | fath-1 | F33D4.4.1 | C25A1.5.1 | Putative sphingolipid delta(4)-desaturase; Acts as a sphingolipid delta(4)-desaturase; Belongs to the fatty acid desaturase type 1 family. DEGS subfamily. | Fatty acid 2-hydroxylase; Catalyzes stereospecific hydroxylation of free fatty acids at the C-2 position to produce (R)-2-hydroxy fatty acids, which are building blocks of sphingolipids and glycosphingolipids common in neural tissue and epidermis. Plays an essential role in the synthesis of galactosphingolipids of the myelin sheath. Responsible for the synthesis of sphingolipids and glycosphingolipids involved in the formation of epidermal lamellar bodies critical for skin permeability barrier. Participates in the synthesis of glycosphingolipids and a fraction of type II wax diesters i [...] | 0.755 |
F33D4.4 | sptl-1 | F33D4.4.1 | C23H3.4a.2 | Putative sphingolipid delta(4)-desaturase; Acts as a sphingolipid delta(4)-desaturase; Belongs to the fatty acid desaturase type 1 family. DEGS subfamily. | Serine palmitoyltransferase 1; Component of the serine palmitoyltransferase (SPT) that catalyzes the first committed step in sphingolipid biosynthesis, which is the condensation of an acyl-CoA species and L-serine. The catalytic core is composed of a heterodimer of sptl-1 and sptl-2 or sptl-1 and sptl-3 (By similarity). Required for the specification of abicobasal polarity and development of the gut lumen. | 0.520 |
F35C8.5 | Y52B11A.3 | F35C8.5.1 | Y52B11A.3a.1 | Cholesterol 25-hydroxylase-like protein; Probable sterol desaturase. | Uncharacterized protein. | 0.404 |
F35C8.5 | agmo-1 | F35C8.5.1 | BE10.2.1 | Cholesterol 25-hydroxylase-like protein; Probable sterol desaturase. | Alkylglycerol monooxygenase; Glyceryl-ether monooxygenase that cleaves the O-alkyl bond of ether lipids; Belongs to the sterol desaturase family. TMEM195 subfamily. | 0.969 |
F35C8.5 | fath-1 | F35C8.5.1 | C25A1.5.1 | Cholesterol 25-hydroxylase-like protein; Probable sterol desaturase. | Fatty acid 2-hydroxylase; Catalyzes stereospecific hydroxylation of free fatty acids at the C-2 position to produce (R)-2-hydroxy fatty acids, which are building blocks of sphingolipids and glycosphingolipids common in neural tissue and epidermis. Plays an essential role in the synthesis of galactosphingolipids of the myelin sheath. Responsible for the synthesis of sphingolipids and glycosphingolipids involved in the formation of epidermal lamellar bodies critical for skin permeability barrier. Participates in the synthesis of glycosphingolipids and a fraction of type II wax diesters i [...] | 0.956 |
F49E12.10 | Y52B11A.3 | F49E12.10.1 | Y52B11A.3a.1 | Fatty acid hydroxylase domain-containing protein; Belongs to the sterol desaturase family. | Uncharacterized protein. | 0.404 |
F49E12.10 | agmo-1 | F49E12.10.1 | BE10.2.1 | Fatty acid hydroxylase domain-containing protein; Belongs to the sterol desaturase family. | Alkylglycerol monooxygenase; Glyceryl-ether monooxygenase that cleaves the O-alkyl bond of ether lipids; Belongs to the sterol desaturase family. TMEM195 subfamily. | 0.969 |
F49E12.10 | fath-1 | F49E12.10.1 | C25A1.5.1 | Fatty acid hydroxylase domain-containing protein; Belongs to the sterol desaturase family. | Fatty acid 2-hydroxylase; Catalyzes stereospecific hydroxylation of free fatty acids at the C-2 position to produce (R)-2-hydroxy fatty acids, which are building blocks of sphingolipids and glycosphingolipids common in neural tissue and epidermis. Plays an essential role in the synthesis of galactosphingolipids of the myelin sheath. Responsible for the synthesis of sphingolipids and glycosphingolipids involved in the formation of epidermal lamellar bodies critical for skin permeability barrier. Participates in the synthesis of glycosphingolipids and a fraction of type II wax diesters i [...] | 0.956 |
Y52B11A.3 | F35C8.5 | Y52B11A.3a.1 | F35C8.5.1 | Uncharacterized protein. | Cholesterol 25-hydroxylase-like protein; Probable sterol desaturase. | 0.404 |
Y52B11A.3 | F49E12.10 | Y52B11A.3a.1 | F49E12.10.1 | Uncharacterized protein. | Fatty acid hydroxylase domain-containing protein; Belongs to the sterol desaturase family. | 0.404 |
Y52B11A.3 | agmo-1 | Y52B11A.3a.1 | BE10.2.1 | Uncharacterized protein. | Alkylglycerol monooxygenase; Glyceryl-ether monooxygenase that cleaves the O-alkyl bond of ether lipids; Belongs to the sterol desaturase family. TMEM195 subfamily. | 0.404 |
Y52B11A.3 | drd-1 | Y52B11A.3a.1 | F49E12.9a.1 | Uncharacterized protein. | Fatty acid hydroxylase domain-containing protein; Belongs to the sterol desaturase family. | 0.404 |
Y52B11A.3 | fath-1 | Y52B11A.3a.1 | C25A1.5.1 | Uncharacterized protein. | Fatty acid 2-hydroxylase; Catalyzes stereospecific hydroxylation of free fatty acids at the C-2 position to produce (R)-2-hydroxy fatty acids, which are building blocks of sphingolipids and glycosphingolipids common in neural tissue and epidermis. Plays an essential role in the synthesis of galactosphingolipids of the myelin sheath. Responsible for the synthesis of sphingolipids and glycosphingolipids involved in the formation of epidermal lamellar bodies critical for skin permeability barrier. Participates in the synthesis of glycosphingolipids and a fraction of type II wax diesters i [...] | 0.781 |
agmo-1 | F35C8.5 | BE10.2.1 | F35C8.5.1 | Alkylglycerol monooxygenase; Glyceryl-ether monooxygenase that cleaves the O-alkyl bond of ether lipids; Belongs to the sterol desaturase family. TMEM195 subfamily. | Cholesterol 25-hydroxylase-like protein; Probable sterol desaturase. | 0.969 |
agmo-1 | F49E12.10 | BE10.2.1 | F49E12.10.1 | Alkylglycerol monooxygenase; Glyceryl-ether monooxygenase that cleaves the O-alkyl bond of ether lipids; Belongs to the sterol desaturase family. TMEM195 subfamily. | Fatty acid hydroxylase domain-containing protein; Belongs to the sterol desaturase family. | 0.969 |
agmo-1 | Y52B11A.3 | BE10.2.1 | Y52B11A.3a.1 | Alkylglycerol monooxygenase; Glyceryl-ether monooxygenase that cleaves the O-alkyl bond of ether lipids; Belongs to the sterol desaturase family. TMEM195 subfamily. | Uncharacterized protein. | 0.404 |
agmo-1 | drd-1 | BE10.2.1 | F49E12.9a.1 | Alkylglycerol monooxygenase; Glyceryl-ether monooxygenase that cleaves the O-alkyl bond of ether lipids; Belongs to the sterol desaturase family. TMEM195 subfamily. | Fatty acid hydroxylase domain-containing protein; Belongs to the sterol desaturase family. | 0.969 |
agmo-1 | fath-1 | BE10.2.1 | C25A1.5.1 | Alkylglycerol monooxygenase; Glyceryl-ether monooxygenase that cleaves the O-alkyl bond of ether lipids; Belongs to the sterol desaturase family. TMEM195 subfamily. | Fatty acid 2-hydroxylase; Catalyzes stereospecific hydroxylation of free fatty acids at the C-2 position to produce (R)-2-hydroxy fatty acids, which are building blocks of sphingolipids and glycosphingolipids common in neural tissue and epidermis. Plays an essential role in the synthesis of galactosphingolipids of the myelin sheath. Responsible for the synthesis of sphingolipids and glycosphingolipids involved in the formation of epidermal lamellar bodies critical for skin permeability barrier. Participates in the synthesis of glycosphingolipids and a fraction of type II wax diesters i [...] | 0.892 |