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ajm-1 protein (Caenorhabditis elegans) - STRING interaction network
"ajm-1" - Apical Junction Molecule in Caenorhabditis elegans
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second shell of interactors
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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ajm-1Apical Junction Molecule; Protein AJM-1, isoform b (1480 aa)    
Predicted Functional Partners:
dlg-1
Drosophila Discs LarGe homolog; Protein DLG-1, isoform a; Belongs to the MAGUK family (967 aa)
     
 
  0.896
hmp-1
Alpha-catenin-like protein hmp-1; Required for cell migration during body enclosure and cell shape changes during body elongation. Required for proper localization of other junctional components, such as pac-1; Belongs to the vinculin/alpha-catenin family (930 aa)
     
   
  0.801
let-413
Protein lap1; Critical role in assembling adherens junctions; adapter protein involved in polarizing protein trafficking in epithelial cells. Necessary to maintain, not establish, the entire terminal web (organelle-depleted, intermediate filament-rich layer of cytoplasm that underlies the apical microvilli of polarized epithelial cells) or brush border assembly at the apical surface gut cells. Required for correct localization of ifb-2 intermediate filaments in the terminal web; Belongs to the LAP (LRR and PDZ) protein family (699 aa)
     
   
  0.797
scm-1
Secretory carrier-associated membrane protein; Protein SCM-1 (scm-1) mRNA, complete cds (335 aa)
           
  0.795
jac-1
Juxtamembrane domain-associated catenin; May act as a positive modulator of hmr-1 function during epidermal morphogenesis. Required for proper localization of other junctional components, such as pac-1; Belongs to the beta-catenin family (1254 aa)
     
   
  0.707
hmr-1
Cadherin-related hmr-1; Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. Required for adherens junction assembly and connecting adherens junctions to the cytoskeleton (2920 aa)
     
   
  0.701
unc-119
Protein unc-119; Myristoyl-binding protein that acts as a cargo adapter- specifically binds the myristoyl moiety of a subset of N- terminally myristoylated proteins and is required for their localization. Plays a key role in ciliary membrane localization of proteins. Required for the establishment or function of the nervous system (244 aa)
           
  0.691
vab-10
Protein VAB-10, isoform g (vab-10) mRNA, complete cds (4955 aa)
     
   
  0.686
vab-9
Protein VAB-9 (vab-9) mRNA, complete cds (211 aa)
     
   
  0.672
ifb-2
Intermediate filament protein ifb-2; Cytoplasmic intermediate filaments provide mechanical strength to cells. Not essential protein. Component of the terminal web (organelle-depleted, intermediate filament-rich layer of cytoplasm that underlies the apical microvilli of polarized epithelial cells) in embryonic through to adult gut cells. Correct localization of filaments requires let-413 (577 aa)
     
   
  0.661
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Caenorhabditis elegans, Rhabditis elegans, roundworm
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