node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
B0511.7 | C25A6.1 | B0511.7.1 | C25A6.1.1 | FHA domain-containing protein. | Serine/threonine-protein phosphatase. | 0.515 |
C25A6.1 | B0511.7 | C25A6.1.1 | B0511.7.1 | Serine/threonine-protein phosphatase. | FHA domain-containing protein. | 0.515 |
C25A6.1 | cpsf-1 | C25A6.1.1 | Y76B12C.7a.1 | Serine/threonine-protein phosphatase. | Probable cleavage and polyadenylation specificity factor subunit 1; CPSF plays a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A)polymerase and other factors to bring about cleavage and poly(A) addition. This subunit is involved in the RNA recognition step of the polyadenylation reaction (By similarity). | 0.498 |
C25A6.1 | cpsf-2 | C25A6.1.1 | F09G2.4.1 | Serine/threonine-protein phosphatase. | Probable cleavage and polyadenylation specificity factor subunit 2; CPSF plays a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A)polymerase and other factors to bring about cleavage and poly(A) addition. | 0.502 |
C25A6.1 | cpsf-3 | C25A6.1.1 | Y67H2A.1.1 | Serine/threonine-protein phosphatase. | Cleavage and Polyadenylation Specificity Factor. | 0.521 |
C25A6.1 | mel-11 | C25A6.1.1 | C06C3.1c.1 | Serine/threonine-protein phosphatase. | ANK_REP_REGION domain-containing protein. | 0.539 |
C25A6.1 | pfs-2 | C25A6.1.1 | R06A4.9a.1 | Serine/threonine-protein phosphatase. | pre-mRNA 3' end processing protein pfs-2; Essential for both cleavage and polyadenylation of pre-mRNA 3' ends (By similarity). Involved in neuron development, probably by regulating pre-mRNA 3'-end processing. | 0.494 |
C25A6.1 | ssup-72 | C25A6.1.1 | T13C2.4.1 | Serine/threonine-protein phosphatase. | RNA polymerase II subunit A C-terminal domain phosphatase ssup-72; Protein phosphatase that dephosphorylates 'Ser-5' of the heptad repeats YSPTSPS in the C-terminal domain of the large RNA polymerase II subunit ama-1. By regulating the phosphorylation status of ama-1 and thus ama-1 binding to specific polyadenylation sites, regulates alternative polyadenylation of pre- mRNAs, including unc-44 and dlk-1 mRNAs. This results in the tissue-specific expression of unc-44 isoforms. | 0.553 |
C25A6.1 | swd-2.1 | C25A6.1.1 | C33H5.6.1 | Serine/threonine-protein phosphatase. | WD_REPEATS_REGION domain-containing protein. | 0.458 |
C25A6.1 | symk-1 | C25A6.1.1 | F25G6.2.1 | Serine/threonine-protein phosphatase. | SYMpleKin cleavage and polyadenylation factor. | 0.504 |
C25A6.1 | tag-307 | C25A6.1.1 | ZK652.10.1 | Serine/threonine-protein phosphatase. | ApaG domain-containing protein. | 0.494 |
cpsf-1 | C25A6.1 | Y76B12C.7a.1 | C25A6.1.1 | Probable cleavage and polyadenylation specificity factor subunit 1; CPSF plays a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A)polymerase and other factors to bring about cleavage and poly(A) addition. This subunit is involved in the RNA recognition step of the polyadenylation reaction (By similarity). | Serine/threonine-protein phosphatase. | 0.498 |
cpsf-1 | cpsf-2 | Y76B12C.7a.1 | F09G2.4.1 | Probable cleavage and polyadenylation specificity factor subunit 1; CPSF plays a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A)polymerase and other factors to bring about cleavage and poly(A) addition. This subunit is involved in the RNA recognition step of the polyadenylation reaction (By similarity). | Probable cleavage and polyadenylation specificity factor subunit 2; CPSF plays a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A)polymerase and other factors to bring about cleavage and poly(A) addition. | 0.999 |
cpsf-1 | cpsf-3 | Y76B12C.7a.1 | Y67H2A.1.1 | Probable cleavage and polyadenylation specificity factor subunit 1; CPSF plays a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A)polymerase and other factors to bring about cleavage and poly(A) addition. This subunit is involved in the RNA recognition step of the polyadenylation reaction (By similarity). | Cleavage and Polyadenylation Specificity Factor. | 0.999 |
cpsf-1 | pfs-2 | Y76B12C.7a.1 | R06A4.9a.1 | Probable cleavage and polyadenylation specificity factor subunit 1; CPSF plays a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A)polymerase and other factors to bring about cleavage and poly(A) addition. This subunit is involved in the RNA recognition step of the polyadenylation reaction (By similarity). | pre-mRNA 3' end processing protein pfs-2; Essential for both cleavage and polyadenylation of pre-mRNA 3' ends (By similarity). Involved in neuron development, probably by regulating pre-mRNA 3'-end processing. | 0.998 |
cpsf-1 | ssup-72 | Y76B12C.7a.1 | T13C2.4.1 | Probable cleavage and polyadenylation specificity factor subunit 1; CPSF plays a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A)polymerase and other factors to bring about cleavage and poly(A) addition. This subunit is involved in the RNA recognition step of the polyadenylation reaction (By similarity). | RNA polymerase II subunit A C-terminal domain phosphatase ssup-72; Protein phosphatase that dephosphorylates 'Ser-5' of the heptad repeats YSPTSPS in the C-terminal domain of the large RNA polymerase II subunit ama-1. By regulating the phosphorylation status of ama-1 and thus ama-1 binding to specific polyadenylation sites, regulates alternative polyadenylation of pre- mRNAs, including unc-44 and dlk-1 mRNAs. This results in the tissue-specific expression of unc-44 isoforms. | 0.991 |
cpsf-1 | swd-2.1 | Y76B12C.7a.1 | C33H5.6.1 | Probable cleavage and polyadenylation specificity factor subunit 1; CPSF plays a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A)polymerase and other factors to bring about cleavage and poly(A) addition. This subunit is involved in the RNA recognition step of the polyadenylation reaction (By similarity). | WD_REPEATS_REGION domain-containing protein. | 0.890 |
cpsf-1 | symk-1 | Y76B12C.7a.1 | F25G6.2.1 | Probable cleavage and polyadenylation specificity factor subunit 1; CPSF plays a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A)polymerase and other factors to bring about cleavage and poly(A) addition. This subunit is involved in the RNA recognition step of the polyadenylation reaction (By similarity). | SYMpleKin cleavage and polyadenylation factor. | 0.999 |
cpsf-2 | C25A6.1 | F09G2.4.1 | C25A6.1.1 | Probable cleavage and polyadenylation specificity factor subunit 2; CPSF plays a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A)polymerase and other factors to bring about cleavage and poly(A) addition. | Serine/threonine-protein phosphatase. | 0.502 |
cpsf-2 | cpsf-1 | F09G2.4.1 | Y76B12C.7a.1 | Probable cleavage and polyadenylation specificity factor subunit 2; CPSF plays a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A)polymerase and other factors to bring about cleavage and poly(A) addition. | Probable cleavage and polyadenylation specificity factor subunit 1; CPSF plays a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A)polymerase and other factors to bring about cleavage and poly(A) addition. This subunit is involved in the RNA recognition step of the polyadenylation reaction (By similarity). | 0.999 |