STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
srsx-34Serpentine Receptor, class SX. (491 aa)    
Predicted Functional Partners:
nceh-1
Neutral Cholesterol Ester Hydrolase homolog.
   
  
 0.701
nhr-61
Nuclear hormone receptor family member nhr-61; Orphan nuclear receptor.
      
 0.698
mans-3
alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family.
      
 0.697
kin-14
Tyrosine-protein kinase.
      
 0.694
tsen-54
tRNA_int_end_N2 domain-containing protein.
      
 0.692
hrpu-1
B30.2/SPRY domain-containing protein.
      
 0.690
ceh-88
Homeobox domain-containing protein.
      
 0.660
scrm-4
Phospholipid scramblase; May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. Belongs to the phospholipid scramblase family.
      
 0.660
tbx-33
Putative T-box protein 33.
      
 0.660
cpsf-1
Probable cleavage and polyadenylation specificity factor subunit 1; CPSF plays a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A)polymerase and other factors to bring about cleavage and poly(A) addition. This subunit is involved in the RNA recognition step of the polyadenylation reaction (By similarity).
      
 0.660
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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