STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
eif-2DEukaryotic Initiation Factor. (549 aa)    
Predicted Functional Partners:
abce-1
ABC transporter, class E.
     
 0.884
rps-30
40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family.
    
 
 0.883
rack-1
Guanine nucleotide-binding protein subunit beta-2-like 1; Required for the expression of antimicrobial peptide nlp-29 in response to fungal infection or physical injury.
    
   0.851
eif-1
SUI1 domain-containing protein.
    
 
 0.841
rps-0
40S ribosomal protein SA; Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA- precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits.
   
 
 0.808
rps-4
40S ribosomal protein S4; Belongs to the eukaryotic ribosomal protein eS4 family.
    
 
 0.807
alh-13
Probable delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family.
    
  0.798
rps-3
40S ribosomal protein S3; Belongs to the universal ribosomal protein uS3 family.
    
 
 0.764
Y47D3A.21
Density-regulated protein homolog; Belongs to the DENR family.
    
 
 0.703
rps-13
40S ribosomal protein S13; Belongs to the universal ribosomal protein uS15 family.
    
 
 0.678
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
Server load: low (12%) [HD]