STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nas-36Zinc metalloproteinase nas-36; Metalloprotease (By similarity). Involved in molting, a process during larval stages in which a new cuticle is formed and the old cuticle is shed. (617 aa)    
Predicted Functional Partners:
col-124
Col_cuticle_N domain-containing protein.
    
 
 0.666
col-91
Putative cuticle collagen 91; Nematode cuticles are composed largely of collagen-like proteins. The cuticle functions both as an exoskeleton and as a barrier to protect the worm from its environment (By similarity).
   
  
 0.637
noah-2
NOmpA Homolog (Drosophila nompA: no mechanoreceptor potential A).
   
 
 0.560
bed-3
Zinc finger BED domain-containing protein 3; Probable transcription factor involved in vulval organogenesis. During vulval development, may play a role in the regulation of cell cycle regulators such as cul-1. Plays a role in larval molting.
   
  
 0.489
nas-3
Zinc metalloproteinase nas-3; Metalloprotease.
  
   
 0.479
pat-12
annotation not available
      
 0.463
tsp-1
Tetraspanin-1.
      
 0.461
mlt-10
Uncharacterized protein.
   
  
 0.448
ptr-8
SSD domain-containing protein.
      
 0.426
T24C12.4
Uncharacterized protein.
   
    0.416
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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