STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hel-1Spliceosome RNA helicase DDX39B homolog; Required for mRNA export out of the nucleus. May play a role in spliceosome assembly. (425 aa)    
Predicted Functional Partners:
thoc-2
THO Complex (Transcription factor/nuclear export) subunit.
   
 0.996
C02B10.4
RRM domain-containing protein.
   
 0.990
aly-1
FoP_duplication domain-containing protein.
   
 0.989
aly-3
FoP_duplication domain-containing protein.
   
 0.989
aly-2
FoP_duplication domain-containing protein.
   
 0.987
rnp-4
RNA-binding protein 8A; Core component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junctions on mRNAs.
   
 0.977
thoc-1
THO Complex (Transcription factor/nuclear export) subunit.
   
 0.968
thoc-5
THO Complex (Transcription factor/nuclear export) subunit.
   
 0.968
Y53G8AR.6
SAP domain-containing protein.
   
 0.968
thoc-7
THO Complex (Transcription factor/nuclear export) subunit.
   
 0.962
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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