node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
aff-1 | ajm-1 | C44B7.3.1 | C25A11.4f.1 | Cell fusion protein aff-1; Required for cell fusion events during development including the fusion of anchor cells (AC), vulval A and vulval D rings, and late epidermal seam cells. Required for amphid sheath cell fusion induced by entry into dauer stage. | Apical junction molecule; Controls adherens junction integrity. Required for the correct rate and completion of elongation of the embryos. | 0.453 |
aff-1 | eff-1 | C44B7.3.1 | C26D10.5a.1 | Cell fusion protein aff-1; Required for cell fusion events during development including the fusion of anchor cells (AC), vulval A and vulval D rings, and late epidermal seam cells. Required for amphid sheath cell fusion induced by entry into dauer stage. | Epithelial Fusion Failure. | 0.402 |
ajm-1 | aff-1 | C25A11.4f.1 | C44B7.3.1 | Apical junction molecule; Controls adherens junction integrity. Required for the correct rate and completion of elongation of the embryos. | Cell fusion protein aff-1; Required for cell fusion events during development including the fusion of anchor cells (AC), vulval A and vulval D rings, and late epidermal seam cells. Required for amphid sheath cell fusion induced by entry into dauer stage. | 0.453 |
ajm-1 | eff-1 | C25A11.4f.1 | C26D10.5a.1 | Apical junction molecule; Controls adherens junction integrity. Required for the correct rate and completion of elongation of the embryos. | Epithelial Fusion Failure. | 0.405 |
bicd-1 | eff-1 | C43G2.2a.1 | C26D10.5a.1 | Protein bicaudal D homolog; Part of a complex with dlc-1 and egal-1, which is recruited to the nuclear envelope by unc-83, where in turn, it recruits dynein to the nuclear surface and regulates nuclear migration in hypodermal precursor cells (Probable). Required for the formation of dendritic branches of PVD sensory neurons ; Belongs to the BicD family. | Epithelial Fusion Failure. | 0.503 |
eff-1 | aff-1 | C26D10.5a.1 | C44B7.3.1 | Epithelial Fusion Failure. | Cell fusion protein aff-1; Required for cell fusion events during development including the fusion of anchor cells (AC), vulval A and vulval D rings, and late epidermal seam cells. Required for amphid sheath cell fusion induced by entry into dauer stage. | 0.402 |
eff-1 | ajm-1 | C26D10.5a.1 | C25A11.4f.1 | Epithelial Fusion Failure. | Apical junction molecule; Controls adherens junction integrity. Required for the correct rate and completion of elongation of the embryos. | 0.405 |
eff-1 | bicd-1 | C26D10.5a.1 | C43G2.2a.1 | Epithelial Fusion Failure. | Protein bicaudal D homolog; Part of a complex with dlc-1 and egal-1, which is recruited to the nuclear envelope by unc-83, where in turn, it recruits dynein to the nuclear surface and regulates nuclear migration in hypodermal precursor cells (Probable). Required for the formation of dendritic branches of PVD sensory neurons ; Belongs to the BicD family. | 0.503 |
eff-1 | egl-26 | C26D10.5a.1 | C23H3.1a.1 | Epithelial Fusion Failure. | LRAT domain-containing protein. | 0.549 |
eff-1 | syx-2 | C26D10.5a.1 | F48F7.2.2 | Epithelial Fusion Failure. | Putative syntaxin-2; Potentially involved in docking of synaptic vesicles at presynaptic active zones; Belongs to the syntaxin family. | 0.680 |
eff-1 | ttr-52 | C26D10.5a.1 | F11F1.7.1 | Epithelial Fusion Failure. | Transthyretin-like protein 52; Plays a role as a bridging molecule that mediates recognition and engulfment of apoptotic cells by cross-linking the surface-exposed phosphatidylserine with the extracellular domain of the phagocyte receptor ced-1. Important for the generation of extracellular phosphatidylserine vesicles that promote loss of the exoplasmic leaflet from apoptotic cells in a time-dependent manner. Required for the exposure of exoplasmic leaflet on the phagocytic cells surrounding the apoptotic cells. Does not affect the phosphatidylserine externalization in living cells. Ma [...] | 0.669 |
eff-1 | unc-89 | C26D10.5a.1 | C09D1.1b.1 | Epithelial Fusion Failure. | Muscle M-line assembly protein unc-89; Structural component of the muscle M line which is involved in assembly and organization of sarcomere myofilaments. The large isoform a, isoform b, isoform d and isoform f play an essential role in maintaining the organization of sarcomeres but not myofilament alignment during body wall muscle development whereas the small isoform c and isoform d appear to have a minor role. Isoform b and isoform f are required for the organization of unc-15/paramyosin into sarcomere thick filaments in body wall muscles. By binding mel-26, a substrate adapter of t [...] | 0.529 |
egl-26 | eff-1 | C23H3.1a.1 | C26D10.5a.1 | LRAT domain-containing protein. | Epithelial Fusion Failure. | 0.549 |
syx-2 | eff-1 | F48F7.2.2 | C26D10.5a.1 | Putative syntaxin-2; Potentially involved in docking of synaptic vesicles at presynaptic active zones; Belongs to the syntaxin family. | Epithelial Fusion Failure. | 0.680 |
ttr-52 | eff-1 | F11F1.7.1 | C26D10.5a.1 | Transthyretin-like protein 52; Plays a role as a bridging molecule that mediates recognition and engulfment of apoptotic cells by cross-linking the surface-exposed phosphatidylserine with the extracellular domain of the phagocyte receptor ced-1. Important for the generation of extracellular phosphatidylserine vesicles that promote loss of the exoplasmic leaflet from apoptotic cells in a time-dependent manner. Required for the exposure of exoplasmic leaflet on the phagocytic cells surrounding the apoptotic cells. Does not affect the phosphatidylserine externalization in living cells. Ma [...] | Epithelial Fusion Failure. | 0.669 |
unc-89 | eff-1 | C09D1.1b.1 | C26D10.5a.1 | Muscle M-line assembly protein unc-89; Structural component of the muscle M line which is involved in assembly and organization of sarcomere myofilaments. The large isoform a, isoform b, isoform d and isoform f play an essential role in maintaining the organization of sarcomeres but not myofilament alignment during body wall muscle development whereas the small isoform c and isoform d appear to have a minor role. Isoform b and isoform f are required for the organization of unc-15/paramyosin into sarcomere thick filaments in body wall muscles. By binding mel-26, a substrate adapter of t [...] | Epithelial Fusion Failure. | 0.529 |