STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
flh-2FLYWCH-type domain-containing protein. (470 aa)    
Predicted Functional Partners:
peb-1
FLYWCH-type domain-containing protein.
   
  
 0.761
rbm-28
RNA Binding Motif protein homolog.
      
 0.695
lsl-1
LSY-2-Like.
      
 0.694
miz-1
SP-RING-type domain-containing protein.
   
  
 0.670
attf-5
AT hook Transcription Factor family.
   
  
 0.668
gfi-3
Protein gfi-3; Probable component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins. Required for the metaphase to anaphase transition in meiosis.
      
 0.665
ztf-8
Zinc finger putative Transcription Factor family.
   
  
 0.591
somi-1
Suppressor of Overexpressed MIcro-RNA.
   
  
 0.541
flh-3
FLYWCH-type domain-containing protein.
   
 
0.512
flh-1
FLYWCH-type domain-containing protein.
   
 
0.483
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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