node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
bam-2 | igcm-1 | Y71F9AR.1.1 | F39H12.4.1 | Neurexin-related protein bam-2; Maintains the normal guidance and termination of axonal branches of VC motorneurons. By associating with cell adhesion protein casy-1, mediates axonal interactions to establish synaptic connections between the male-specific sensory neuron HOA and the AVG interneuron. Plays a role in regulating male mating behavior. | ImmunoGlobulin-like Cell adhesion Molecule family. | 0.499 |
bam-2 | syg-1 | Y71F9AR.1.1 | K02E10.8b.1 | Neurexin-related protein bam-2; Maintains the normal guidance and termination of axonal branches of VC motorneurons. By associating with cell adhesion protein casy-1, mediates axonal interactions to establish synaptic connections between the male-specific sensory neuron HOA and the AVG interneuron. Plays a role in regulating male mating behavior. | Synaptogenesis protein syg-1; Cell adhesion protein. Involved in synapse formation in the HSNL egg-laying motor neuron. Inhibits assembly of the SCF(sel-10) E3 ubiquitin ligase complex at synapses, and protects them from elimination. Also required for F- actin assembly at the synaptic region and for axon branch formation. | 0.481 |
bam-2 | syg-2 | Y71F9AR.1.1 | C26G2.1b.1 | Neurexin-related protein bam-2; Maintains the normal guidance and termination of axonal branches of VC motorneurons. By associating with cell adhesion protein casy-1, mediates axonal interactions to establish synaptic connections between the male-specific sensory neuron HOA and the AVG interneuron. Plays a role in regulating male mating behavior. | Synaptogenesis protein syg-2; Cell adhesion protein. Determines synapse formation. Required for correct localization of syg-1 at synaptic sites. | 0.714 |
igcm-1 | bam-2 | F39H12.4.1 | Y71F9AR.1.1 | ImmunoGlobulin-like Cell adhesion Molecule family. | Neurexin-related protein bam-2; Maintains the normal guidance and termination of axonal branches of VC motorneurons. By associating with cell adhesion protein casy-1, mediates axonal interactions to establish synaptic connections between the male-specific sensory neuron HOA and the AVG interneuron. Plays a role in regulating male mating behavior. | 0.499 |
igcm-1 | nck-1 | F39H12.4.1 | ZK470.5a.1 | ImmunoGlobulin-like Cell adhesion Molecule family. | NCK (Non-Catalytic region of tyrosine Kinase) adaptor protein family. | 0.607 |
igcm-1 | pes-7 | F39H12.4.1 | F09C3.1.1 | ImmunoGlobulin-like Cell adhesion Molecule family. | Patterned Expression Site. | 0.597 |
igcm-1 | syg-1 | F39H12.4.1 | K02E10.8b.1 | ImmunoGlobulin-like Cell adhesion Molecule family. | Synaptogenesis protein syg-1; Cell adhesion protein. Involved in synapse formation in the HSNL egg-laying motor neuron. Inhibits assembly of the SCF(sel-10) E3 ubiquitin ligase complex at synapses, and protects them from elimination. Also required for F- actin assembly at the synaptic region and for axon branch formation. | 0.892 |
igcm-1 | syg-2 | F39H12.4.1 | C26G2.1b.1 | ImmunoGlobulin-like Cell adhesion Molecule family. | Synaptogenesis protein syg-2; Cell adhesion protein. Determines synapse formation. Required for correct localization of syg-1 at synaptic sites. | 0.802 |
nck-1 | igcm-1 | ZK470.5a.1 | F39H12.4.1 | NCK (Non-Catalytic region of tyrosine Kinase) adaptor protein family. | ImmunoGlobulin-like Cell adhesion Molecule family. | 0.607 |
nck-1 | pes-7 | ZK470.5a.1 | F09C3.1.1 | NCK (Non-Catalytic region of tyrosine Kinase) adaptor protein family. | Patterned Expression Site. | 0.438 |
nck-1 | syg-1 | ZK470.5a.1 | K02E10.8b.1 | NCK (Non-Catalytic region of tyrosine Kinase) adaptor protein family. | Synaptogenesis protein syg-1; Cell adhesion protein. Involved in synapse formation in the HSNL egg-laying motor neuron. Inhibits assembly of the SCF(sel-10) E3 ubiquitin ligase complex at synapses, and protects them from elimination. Also required for F- actin assembly at the synaptic region and for axon branch formation. | 0.673 |
nck-1 | syg-2 | ZK470.5a.1 | C26G2.1b.1 | NCK (Non-Catalytic region of tyrosine Kinase) adaptor protein family. | Synaptogenesis protein syg-2; Cell adhesion protein. Determines synapse formation. Required for correct localization of syg-1 at synaptic sites. | 0.783 |
nck-1 | unc-40 | ZK470.5a.1 | T19B4.7.1 | NCK (Non-Catalytic region of tyrosine Kinase) adaptor protein family. | Unc-40 protein. | 0.615 |
pes-7 | igcm-1 | F09C3.1.1 | F39H12.4.1 | Patterned Expression Site. | ImmunoGlobulin-like Cell adhesion Molecule family. | 0.597 |
pes-7 | nck-1 | F09C3.1.1 | ZK470.5a.1 | Patterned Expression Site. | NCK (Non-Catalytic region of tyrosine Kinase) adaptor protein family. | 0.438 |
pes-7 | syg-1 | F09C3.1.1 | K02E10.8b.1 | Patterned Expression Site. | Synaptogenesis protein syg-1; Cell adhesion protein. Involved in synapse formation in the HSNL egg-laying motor neuron. Inhibits assembly of the SCF(sel-10) E3 ubiquitin ligase complex at synapses, and protects them from elimination. Also required for F- actin assembly at the synaptic region and for axon branch formation. | 0.516 |
pes-7 | syg-2 | F09C3.1.1 | C26G2.1b.1 | Patterned Expression Site. | Synaptogenesis protein syg-2; Cell adhesion protein. Determines synapse formation. Required for correct localization of syg-1 at synaptic sites. | 0.669 |
sad-1 | syd-1 | F15A2.6a.1 | F35D2.5a.1 | Serine/threonine kinase SAD-1; Regulates both neuronal polarity and synaptic organization when bound to strd-1. Kinase activity is required for the establishment, but not the maintenance, of both processes. Binding to nab-1 is essential for role in restricting axonal fate during neuronal polarization but is not required for regulating synapse morphology. | Rho GTPase-activating protein syd-1; Probable GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state. Regulates the localization and assembly of presynaptic components during presynaptic development and is required for specifying the identity of axons during initial polarity acquisition. In these roles it is thought to act cell autonomously downstream of syg-1 and syg-2 and upstream of syd-2, possibly as a positive regulator of the latter. Required for the control of movement, egg-laying and the correct localization of elks-1. | 0.804 |
sad-1 | syd-2 | F15A2.6a.1 | F59F5.6.1 | Serine/threonine kinase SAD-1; Regulates both neuronal polarity and synaptic organization when bound to strd-1. Kinase activity is required for the establishment, but not the maintenance, of both processes. Binding to nab-1 is essential for role in restricting axonal fate during neuronal polarization but is not required for regulating synapse morphology. | Liprin-alpha; May play a role in regulating the structure of the neuronal region, called the active zone, from which synaptic vesicles send neurotransmitter signals across the synapse. This may be in association with the liprin-beta protein hlb-1 ; Belongs to the liprin family. Liprin-alpha subfamily. | 0.777 |
sad-1 | syg-1 | F15A2.6a.1 | K02E10.8b.1 | Serine/threonine kinase SAD-1; Regulates both neuronal polarity and synaptic organization when bound to strd-1. Kinase activity is required for the establishment, but not the maintenance, of both processes. Binding to nab-1 is essential for role in restricting axonal fate during neuronal polarization but is not required for regulating synapse morphology. | Synaptogenesis protein syg-1; Cell adhesion protein. Involved in synapse formation in the HSNL egg-laying motor neuron. Inhibits assembly of the SCF(sel-10) E3 ubiquitin ligase complex at synapses, and protects them from elimination. Also required for F- actin assembly at the synaptic region and for axon branch formation. | 0.621 |