Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| C27A12.2 | ari-1.2 | C27A12.2.1 | C27A12.7a.1 | Suppressor of ZYg-1. | RBR-type E3 ubiquitin transferase. | 0.822 |
| C27A12.2 | msp-142 | C27A12.2.1 | K05F1.2.1 | Suppressor of ZYg-1. | Major sperm protein 19/31/40/45/50/51/53/59/61/65/81/113/142. | 0.576 |
| F16B4.6 | ari-1.2 | F16B4.6a.1 | C27A12.7a.1 | Uncharacterized protein. | RBR-type E3 ubiquitin transferase. | 0.591 |
| ari-1.2 | C27A12.2 | C27A12.7a.1 | C27A12.2.1 | RBR-type E3 ubiquitin transferase. | Suppressor of ZYg-1. | 0.822 |
| ari-1.2 | F16B4.6 | C27A12.7a.1 | F16B4.6a.1 | RBR-type E3 ubiquitin transferase. | Uncharacterized protein. | 0.591 |
| ari-1.2 | cul-1 | C27A12.7a.1 | D2045.6.1 | RBR-type E3 ubiquitin transferase. | Cullin-1; Probable core component of multiple cullin-RING-based SCF (SKP1-CUL1-F-box) E3 ubiquitin-protein ligase complexes which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. As a scaffold protein may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. Required for developmentally programmed transitions from the G1 phase of the cell cycle to the G0 phase or the apoptotic pathway. | 0.579 |
| ari-1.2 | cul-3 | C27A12.7a.1 | Y108G3AL.1a.3 | RBR-type E3 ubiquitin transferase. | Cullin-3; Probable core component of multiple cullin-RING-based BCB (BTB-CUL3-BTB) E3 ubiquitin-protein ligase complexes which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. Probably acts as a scaffold protein which may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. Required to target mei-3/katanin for degradation at the meiosis to mitosis transition via its neddylation and deneddylation. Functions in ubiquitin-mediated degradation of CKIs to target cki-1 for degradation. Regulates microtubule st [...] | 0.634 |
| ari-1.2 | cul-6 | C27A12.7a.1 | K08E7.7a.1 | RBR-type E3 ubiquitin transferase. | Cullin-6; Probable core component of cullin-based SCF-like E3 ubiquitin-protein ligase complexes which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. | 0.564 |
| ari-1.2 | msp-142 | C27A12.7a.1 | K05F1.2.1 | RBR-type E3 ubiquitin transferase. | Major sperm protein 19/31/40/45/50/51/53/59/61/65/81/113/142. | 0.531 |
| ari-1.2 | ned-8 | C27A12.7a.1 | F45H11.2.1 | RBR-type E3 ubiquitin transferase. | NEDD8; Ubiquitin-like protein which plays an important role in cell cycle control and embryogenesis. Covalent attachment to its substrates requires prior activation by the E1 complex uba-3-ula-1 and linkage to the E2 enzyme ubc-12. Attachment of ned-8 to cullins activates their associated E3 ubiquitin ligase activity, and thus promotes polyubiquitination and proteasomal degradation of cyclins and other regulatory proteins. | 0.590 |
| ari-1.2 | rbx-1 | C27A12.7a.1 | ZK287.5.2 | RBR-type E3 ubiquitin transferase. | RING-box protein 1; Component of the SCF (SKP1-CUL1-F-box protein) E3 ubiquitin ligase complex, which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Through the RING-type zinc finger, seems to recruit the E2 ubiquitination enzyme to the complex and brings it into close proximity to the substrate (By similarity). Essential for meiosis, mitotic chromosomal condensation and cytokinesis. Involved in histone H3 phosphorylation. | 0.614 |
| ari-1.2 | ubc-18 | C27A12.7a.1 | R01H2.6.1 | RBR-type E3 ubiquitin transferase. | UBIQUITIN_CONJUGAT_2 domain-containing protein. | 0.854 |
| ari-1.2 | ubc-22 | C27A12.7a.1 | C06E2.7.1 | RBR-type E3 ubiquitin transferase. | UBiquitin Conjugating enzyme. | 0.570 |
| cul-1 | ari-1.2 | D2045.6.1 | C27A12.7a.1 | Cullin-1; Probable core component of multiple cullin-RING-based SCF (SKP1-CUL1-F-box) E3 ubiquitin-protein ligase complexes which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. As a scaffold protein may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. Required for developmentally programmed transitions from the G1 phase of the cell cycle to the G0 phase or the apoptotic pathway. | RBR-type E3 ubiquitin transferase. | 0.579 |
| cul-1 | cul-3 | D2045.6.1 | Y108G3AL.1a.3 | Cullin-1; Probable core component of multiple cullin-RING-based SCF (SKP1-CUL1-F-box) E3 ubiquitin-protein ligase complexes which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. As a scaffold protein may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. Required for developmentally programmed transitions from the G1 phase of the cell cycle to the G0 phase or the apoptotic pathway. | Cullin-3; Probable core component of multiple cullin-RING-based BCB (BTB-CUL3-BTB) E3 ubiquitin-protein ligase complexes which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. Probably acts as a scaffold protein which may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. Required to target mei-3/katanin for degradation at the meiosis to mitosis transition via its neddylation and deneddylation. Functions in ubiquitin-mediated degradation of CKIs to target cki-1 for degradation. Regulates microtubule st [...] | 0.846 |
| cul-1 | cul-6 | D2045.6.1 | K08E7.7a.1 | Cullin-1; Probable core component of multiple cullin-RING-based SCF (SKP1-CUL1-F-box) E3 ubiquitin-protein ligase complexes which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. As a scaffold protein may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. Required for developmentally programmed transitions from the G1 phase of the cell cycle to the G0 phase or the apoptotic pathway. | Cullin-6; Probable core component of cullin-based SCF-like E3 ubiquitin-protein ligase complexes which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. | 0.907 |
| cul-1 | ned-8 | D2045.6.1 | F45H11.2.1 | Cullin-1; Probable core component of multiple cullin-RING-based SCF (SKP1-CUL1-F-box) E3 ubiquitin-protein ligase complexes which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. As a scaffold protein may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. Required for developmentally programmed transitions from the G1 phase of the cell cycle to the G0 phase or the apoptotic pathway. | NEDD8; Ubiquitin-like protein which plays an important role in cell cycle control and embryogenesis. Covalent attachment to its substrates requires prior activation by the E1 complex uba-3-ula-1 and linkage to the E2 enzyme ubc-12. Attachment of ned-8 to cullins activates their associated E3 ubiquitin ligase activity, and thus promotes polyubiquitination and proteasomal degradation of cyclins and other regulatory proteins. | 0.996 |
| cul-1 | rbx-1 | D2045.6.1 | ZK287.5.2 | Cullin-1; Probable core component of multiple cullin-RING-based SCF (SKP1-CUL1-F-box) E3 ubiquitin-protein ligase complexes which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. As a scaffold protein may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. Required for developmentally programmed transitions from the G1 phase of the cell cycle to the G0 phase or the apoptotic pathway. | RING-box protein 1; Component of the SCF (SKP1-CUL1-F-box protein) E3 ubiquitin ligase complex, which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Through the RING-type zinc finger, seems to recruit the E2 ubiquitination enzyme to the complex and brings it into close proximity to the substrate (By similarity). Essential for meiosis, mitotic chromosomal condensation and cytokinesis. Involved in histone H3 phosphorylation. | 0.999 |
| cul-1 | ubc-18 | D2045.6.1 | R01H2.6.1 | Cullin-1; Probable core component of multiple cullin-RING-based SCF (SKP1-CUL1-F-box) E3 ubiquitin-protein ligase complexes which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. As a scaffold protein may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. Required for developmentally programmed transitions from the G1 phase of the cell cycle to the G0 phase or the apoptotic pathway. | UBIQUITIN_CONJUGAT_2 domain-containing protein. | 0.479 |
| cul-3 | ari-1.2 | Y108G3AL.1a.3 | C27A12.7a.1 | Cullin-3; Probable core component of multiple cullin-RING-based BCB (BTB-CUL3-BTB) E3 ubiquitin-protein ligase complexes which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. Probably acts as a scaffold protein which may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. Required to target mei-3/katanin for degradation at the meiosis to mitosis transition via its neddylation and deneddylation. Functions in ubiquitin-mediated degradation of CKIs to target cki-1 for degradation. Regulates microtubule st [...] | RBR-type E3 ubiquitin transferase. | 0.634 |
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