node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
C27A2.7 | Y56A3A.28 | C27A2.7.1 | Y56A3A.28.1 | Uncharacterized protein. | C2H2-type domain-containing protein. | 0.465 |
C27A2.7 | che-1 | C27A2.7.1 | C55B7.12b.1 | Uncharacterized protein. | Transcription factor che-1; Transcription factor essential for the identity of ASE chemosensory neurons. Acts by activating expression of genes that are specific for ASE chemosensory neurons, such as seven-transmembrane receptors or guanylate cyclase. Also required to control the left/right asymmetry in ASE chemosensory neurons by regulating expression of genes such as cog-1 and ceh-36. | 0.400 |
C27A2.7 | egl-43 | C27A2.7.1 | R53.3a.1 | Uncharacterized protein. | Uncharacterized protein. | 0.400 |
C27A2.7 | his-40 | C27A2.7.1 | K03A1.1.1 | Uncharacterized protein. | Histone H3. | 0.460 |
C27A2.7 | lin-53 | C27A2.7.1 | K07A1.12.1 | Uncharacterized protein. | Probable histone-binding protein lin-53; Core histone-binding subunit that may target chromatin assembly factors, chromatin remodeling factors and histone deacetylases to their histone substrates in a manner that is regulated by nucleosomal DNA (By similarity). Required for hcp-3 and his-1 stabilization, localization of hcp-3 to centromeres and for proper chromosome segregation. Synthetic multivulva class B (synMuvB) protein. SynMuvB proteins are required to repress the induction of vulval development by Ras signaling and probably act by forming the multiprotein DRM complex that repres [...] | 0.585 |
C27A2.7 | mes-2 | C27A2.7.1 | R06A4.7.1 | Uncharacterized protein. | Histone-lysine N-methyltransferase mes-2; Polycomb group (PcG) protein. Catalytic subunit of a the mes- 2/mes-3/mes-6 complex, which methylates 'Lys-27' of histone H3, leading to transcriptional repression of the affected target genes. PcG proteins act by forming multiprotein complexes, which are required to maintain the transcriptionally repressive state of homeotic genes throughout development. PcG proteins are not required to initiate repression, but to maintain it during later stages of development. The mes-2/mes-3/mes-6 complex may participate in the global inactivation of the X c [...] | 0.600 |
C27A2.7 | mes-6 | C27A2.7.1 | C09G4.5.1 | Uncharacterized protein. | Polycomb protein mes-6; Polycomb group (PcG) protein. PcG proteins act by forming multiprotein complexes, which are required to maintain the transcriptionally repressive state of homeotic genes throughout development. PcG proteins are not required to initiate repression, but to maintain it during later stages of development. The mes-2/mes-3/mes- 6 complex may participate in the global inactivation of the X chromosomes in germline cells. The complex may act via methylation of histone H3 'Lys-27', rendering chromatin heritably changed in its expressibility. This complex is required to ex [...] | 0.571 |
C27A2.7 | rba-1 | C27A2.7.1 | K07A1.11.1 | Uncharacterized protein. | Probable histone-binding protein rba-1; Core histone-binding subunit that may target chromatin assembly factors, chromatin remodeling factors and histone deacetylases to their histone substrates in a manner that is regulated by nucleosomal DNA (By similarity). Plays a role in regulating cell cycle progression. Required to repress the induction of vulval development by Ras signaling. In association with the zinc finger protein ztf-11, negatively regulates the expression of non- neuronal genes during neurogenesis. Belongs to the WD repeat RBAP46/RBAP48/MSI1 family. | 0.585 |
Y56A3A.28 | C27A2.7 | Y56A3A.28.1 | C27A2.7.1 | C2H2-type domain-containing protein. | Uncharacterized protein. | 0.465 |
Y56A3A.28 | che-1 | Y56A3A.28.1 | C55B7.12b.1 | C2H2-type domain-containing protein. | Transcription factor che-1; Transcription factor essential for the identity of ASE chemosensory neurons. Acts by activating expression of genes that are specific for ASE chemosensory neurons, such as seven-transmembrane receptors or guanylate cyclase. Also required to control the left/right asymmetry in ASE chemosensory neurons by regulating expression of genes such as cog-1 and ceh-36. | 0.550 |
Y56A3A.28 | egl-43 | Y56A3A.28.1 | R53.3a.1 | C2H2-type domain-containing protein. | Uncharacterized protein. | 0.504 |
Y56A3A.28 | his-40 | Y56A3A.28.1 | K03A1.1.1 | C2H2-type domain-containing protein. | Histone H3. | 0.475 |
Y56A3A.28 | lin-53 | Y56A3A.28.1 | K07A1.12.1 | C2H2-type domain-containing protein. | Probable histone-binding protein lin-53; Core histone-binding subunit that may target chromatin assembly factors, chromatin remodeling factors and histone deacetylases to their histone substrates in a manner that is regulated by nucleosomal DNA (By similarity). Required for hcp-3 and his-1 stabilization, localization of hcp-3 to centromeres and for proper chromosome segregation. Synthetic multivulva class B (synMuvB) protein. SynMuvB proteins are required to repress the induction of vulval development by Ras signaling and probably act by forming the multiprotein DRM complex that repres [...] | 0.505 |
Y56A3A.28 | mes-2 | Y56A3A.28.1 | R06A4.7.1 | C2H2-type domain-containing protein. | Histone-lysine N-methyltransferase mes-2; Polycomb group (PcG) protein. Catalytic subunit of a the mes- 2/mes-3/mes-6 complex, which methylates 'Lys-27' of histone H3, leading to transcriptional repression of the affected target genes. PcG proteins act by forming multiprotein complexes, which are required to maintain the transcriptionally repressive state of homeotic genes throughout development. PcG proteins are not required to initiate repression, but to maintain it during later stages of development. The mes-2/mes-3/mes-6 complex may participate in the global inactivation of the X c [...] | 0.501 |
Y56A3A.28 | mes-6 | Y56A3A.28.1 | C09G4.5.1 | C2H2-type domain-containing protein. | Polycomb protein mes-6; Polycomb group (PcG) protein. PcG proteins act by forming multiprotein complexes, which are required to maintain the transcriptionally repressive state of homeotic genes throughout development. PcG proteins are not required to initiate repression, but to maintain it during later stages of development. The mes-2/mes-3/mes- 6 complex may participate in the global inactivation of the X chromosomes in germline cells. The complex may act via methylation of histone H3 'Lys-27', rendering chromatin heritably changed in its expressibility. This complex is required to ex [...] | 0.515 |
Y56A3A.28 | rba-1 | Y56A3A.28.1 | K07A1.11.1 | C2H2-type domain-containing protein. | Probable histone-binding protein rba-1; Core histone-binding subunit that may target chromatin assembly factors, chromatin remodeling factors and histone deacetylases to their histone substrates in a manner that is regulated by nucleosomal DNA (By similarity). Plays a role in regulating cell cycle progression. Required to repress the induction of vulval development by Ras signaling. In association with the zinc finger protein ztf-11, negatively regulates the expression of non- neuronal genes during neurogenesis. Belongs to the WD repeat RBAP46/RBAP48/MSI1 family. | 0.499 |
che-1 | C27A2.7 | C55B7.12b.1 | C27A2.7.1 | Transcription factor che-1; Transcription factor essential for the identity of ASE chemosensory neurons. Acts by activating expression of genes that are specific for ASE chemosensory neurons, such as seven-transmembrane receptors or guanylate cyclase. Also required to control the left/right asymmetry in ASE chemosensory neurons by regulating expression of genes such as cog-1 and ceh-36. | Uncharacterized protein. | 0.400 |
che-1 | Y56A3A.28 | C55B7.12b.1 | Y56A3A.28.1 | Transcription factor che-1; Transcription factor essential for the identity of ASE chemosensory neurons. Acts by activating expression of genes that are specific for ASE chemosensory neurons, such as seven-transmembrane receptors or guanylate cyclase. Also required to control the left/right asymmetry in ASE chemosensory neurons by regulating expression of genes such as cog-1 and ceh-36. | C2H2-type domain-containing protein. | 0.550 |
che-1 | egl-43 | C55B7.12b.1 | R53.3a.1 | Transcription factor che-1; Transcription factor essential for the identity of ASE chemosensory neurons. Acts by activating expression of genes that are specific for ASE chemosensory neurons, such as seven-transmembrane receptors or guanylate cyclase. Also required to control the left/right asymmetry in ASE chemosensory neurons by regulating expression of genes such as cog-1 and ceh-36. | Uncharacterized protein. | 0.400 |
che-1 | his-40 | C55B7.12b.1 | K03A1.1.1 | Transcription factor che-1; Transcription factor essential for the identity of ASE chemosensory neurons. Acts by activating expression of genes that are specific for ASE chemosensory neurons, such as seven-transmembrane receptors or guanylate cyclase. Also required to control the left/right asymmetry in ASE chemosensory neurons by regulating expression of genes such as cog-1 and ceh-36. | Histone H3. | 0.460 |