STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
C27A7.5ANK_REP_REGION domain-containing protein. (715 aa)    
Predicted Functional Partners:
C39B5.6
Glutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrial; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). Belongs to the GatB/GatE family. GatB subfamily.
    
 0.944
emb-30
Abnormal embryogenesis protein 30; Probable component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle (By similarity). The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins (By similarity). Developmental role in early embryogenesis and the metaphase to anaphase transition in oocyte and spermatocyte meiosis and mitosis in somatic and germ cells. Required for embryonic anterior- posterior axis formation. Negatively regulat [...]
    
   0.916
gmps-1
Probable GMP synthase [glutamine-hydrolyzing].
  
 
  0.880
gdh-1
Glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
  
 
 0.871
ppat-1
Amidophosphoribosyltransferase; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
    
  0.867
Y62E10A.6
NADPH:adrenodoxin oxidoreductase, mitochondrial.
  
 
 0.862
W07E11.1
Glutamine amidotransferase type-2 domain-containing protein.
    
 0.848
pyr-1
Glutamine-dependent carbamoyl-phosphate synthase; This protein is a 'fusion' protein encoding four enzymatic activities of the pyrimidine pathway (GATase, CPSase, ATCase and DHOase) (By similarity). Involved in the elongation of the pharyngeal isthmus during development, probably by providing precursors of UDP- sugars required for heparan sulfate proteoglycan biosynthesis. Regulates the organization of the actin and intermediate filaments cytoskeleton in the pharyngeal muscles ; In the central section; belongs to the metallo-dependent hydrolases superfamily. DHOase family. CAD subfamily.
   
 0.845
gfat-1
Glutamine-Fructose 6-phosphate AminoTransferase homolog.
   
 0.842
gfat-2
Glutamine-Fructose 6-phosphate AminoTransferase homolog.
   
 0.842
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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