node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
asfl-1 | htz-1 | C03D6.5.1 | R08C7.3.3 | Probable histone chaperone asf-1-like protein; Histone chaperone that facilitates histone deposition and histone exchange and removal during nucleosome assembly and disassembly. | Histone H2A.V; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post- translational modifications of histones, also called histone code, and nucleosome remodeling (By similarity). Required to maintain non-distal tip cell (DTC) fate of somatic gonadal [...] | 0.772 |
asfl-1 | nap-1 | C03D6.5.1 | D2096.8.1 | Probable histone chaperone asf-1-like protein; Histone chaperone that facilitates histone deposition and histone exchange and removal during nucleosome assembly and disassembly. | Nucleosome Assembly Protein; Belongs to the nucleosome assembly protein (NAP) family. | 0.451 |
asfl-1 | rba-1 | C03D6.5.1 | K07A1.11.1 | Probable histone chaperone asf-1-like protein; Histone chaperone that facilitates histone deposition and histone exchange and removal during nucleosome assembly and disassembly. | Probable histone-binding protein rba-1; Core histone-binding subunit that may target chromatin assembly factors, chromatin remodeling factors and histone deacetylases to their histone substrates in a manner that is regulated by nucleosomal DNA (By similarity). Plays a role in regulating cell cycle progression. Required to repress the induction of vulval development by Ras signaling. In association with the zinc finger protein ztf-11, negatively regulates the expression of non- neuronal genes during neurogenesis. Belongs to the WD repeat RBAP46/RBAP48/MSI1 family. | 0.855 |
asfl-1 | spr-2 | C03D6.5.1 | C27B7.1b.1 | Probable histone chaperone asf-1-like protein; Histone chaperone that facilitates histone deposition and histone exchange and removal during nucleosome assembly and disassembly. | Suppressor of presenilin-2; Potential corepressor protein, which may affect chromatin structure and/or transcription. May participate in the transcriptional repression of the presenilin protein hop-1. Belongs to the nucleosome assembly protein (NAP) family. | 0.723 |
bub-3 | htz-1 | Y54G9A.6.1 | R08C7.3.3 | Mitotic checkpoint protein bub-3; Has a dual function in spindle-assembly checkpoint signaling and in promoting the establishment of correct kinetochore-microtubule (K-MT) attachments. Promotes the formation of stable end-on bipolar attachments of chromosomes. Necessary for expression and kinetochore localization of bub-1. Plays a role in synapsis checkpoint signaling inducing apoptosis in response to unsynapsed chromosomes and thus controlling chromosomal segregation during oocyte meiosis. | Histone H2A.V; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post- translational modifications of histones, also called histone code, and nucleosome remodeling (By similarity). Required to maintain non-distal tip cell (DTC) fate of somatic gonadal [...] | 0.546 |
bub-3 | rba-1 | Y54G9A.6.1 | K07A1.11.1 | Mitotic checkpoint protein bub-3; Has a dual function in spindle-assembly checkpoint signaling and in promoting the establishment of correct kinetochore-microtubule (K-MT) attachments. Promotes the formation of stable end-on bipolar attachments of chromosomes. Necessary for expression and kinetochore localization of bub-1. Plays a role in synapsis checkpoint signaling inducing apoptosis in response to unsynapsed chromosomes and thus controlling chromosomal segregation during oocyte meiosis. | Probable histone-binding protein rba-1; Core histone-binding subunit that may target chromatin assembly factors, chromatin remodeling factors and histone deacetylases to their histone substrates in a manner that is regulated by nucleosomal DNA (By similarity). Plays a role in regulating cell cycle progression. Required to repress the induction of vulval development by Ras signaling. In association with the zinc finger protein ztf-11, negatively regulates the expression of non- neuronal genes during neurogenesis. Belongs to the WD repeat RBAP46/RBAP48/MSI1 family. | 0.551 |
bub-3 | spr-2 | Y54G9A.6.1 | C27B7.1b.1 | Mitotic checkpoint protein bub-3; Has a dual function in spindle-assembly checkpoint signaling and in promoting the establishment of correct kinetochore-microtubule (K-MT) attachments. Promotes the formation of stable end-on bipolar attachments of chromosomes. Necessary for expression and kinetochore localization of bub-1. Plays a role in synapsis checkpoint signaling inducing apoptosis in response to unsynapsed chromosomes and thus controlling chromosomal segregation during oocyte meiosis. | Suppressor of presenilin-2; Potential corepressor protein, which may affect chromatin structure and/or transcription. May participate in the transcriptional repression of the presenilin protein hop-1. Belongs to the nucleosome assembly protein (NAP) family. | 0.601 |
htz-1 | asfl-1 | R08C7.3.3 | C03D6.5.1 | Histone H2A.V; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post- translational modifications of histones, also called histone code, and nucleosome remodeling (By similarity). Required to maintain non-distal tip cell (DTC) fate of somatic gonadal [...] | Probable histone chaperone asf-1-like protein; Histone chaperone that facilitates histone deposition and histone exchange and removal during nucleosome assembly and disassembly. | 0.772 |
htz-1 | bub-3 | R08C7.3.3 | Y54G9A.6.1 | Histone H2A.V; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post- translational modifications of histones, also called histone code, and nucleosome remodeling (By similarity). Required to maintain non-distal tip cell (DTC) fate of somatic gonadal [...] | Mitotic checkpoint protein bub-3; Has a dual function in spindle-assembly checkpoint signaling and in promoting the establishment of correct kinetochore-microtubule (K-MT) attachments. Promotes the formation of stable end-on bipolar attachments of chromosomes. Necessary for expression and kinetochore localization of bub-1. Plays a role in synapsis checkpoint signaling inducing apoptosis in response to unsynapsed chromosomes and thus controlling chromosomal segregation during oocyte meiosis. | 0.546 |
htz-1 | nap-1 | R08C7.3.3 | D2096.8.1 | Histone H2A.V; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post- translational modifications of histones, also called histone code, and nucleosome remodeling (By similarity). Required to maintain non-distal tip cell (DTC) fate of somatic gonadal [...] | Nucleosome Assembly Protein; Belongs to the nucleosome assembly protein (NAP) family. | 0.996 |
htz-1 | rba-1 | R08C7.3.3 | K07A1.11.1 | Histone H2A.V; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post- translational modifications of histones, also called histone code, and nucleosome remodeling (By similarity). Required to maintain non-distal tip cell (DTC) fate of somatic gonadal [...] | Probable histone-binding protein rba-1; Core histone-binding subunit that may target chromatin assembly factors, chromatin remodeling factors and histone deacetylases to their histone substrates in a manner that is regulated by nucleosomal DNA (By similarity). Plays a role in regulating cell cycle progression. Required to repress the induction of vulval development by Ras signaling. In association with the zinc finger protein ztf-11, negatively regulates the expression of non- neuronal genes during neurogenesis. Belongs to the WD repeat RBAP46/RBAP48/MSI1 family. | 0.576 |
htz-1 | spr-2 | R08C7.3.3 | C27B7.1b.1 | Histone H2A.V; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post- translational modifications of histones, also called histone code, and nucleosome remodeling (By similarity). Required to maintain non-distal tip cell (DTC) fate of somatic gonadal [...] | Suppressor of presenilin-2; Potential corepressor protein, which may affect chromatin structure and/or transcription. May participate in the transcriptional repression of the presenilin protein hop-1. Belongs to the nucleosome assembly protein (NAP) family. | 0.876 |
htz-1 | unc-85 | R08C7.3.3 | F10G7.3.1 | Histone H2A.V; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post- translational modifications of histones, also called histone code, and nucleosome remodeling (By similarity). Required to maintain non-distal tip cell (DTC) fate of somatic gonadal [...] | Probable histone chaperone asf-1; Histone chaperone that facilitates histone deposition and histone exchange and removal during nucleosome assembly and disassembly. | 0.773 |
nap-1 | asfl-1 | D2096.8.1 | C03D6.5.1 | Nucleosome Assembly Protein; Belongs to the nucleosome assembly protein (NAP) family. | Probable histone chaperone asf-1-like protein; Histone chaperone that facilitates histone deposition and histone exchange and removal during nucleosome assembly and disassembly. | 0.451 |
nap-1 | htz-1 | D2096.8.1 | R08C7.3.3 | Nucleosome Assembly Protein; Belongs to the nucleosome assembly protein (NAP) family. | Histone H2A.V; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post- translational modifications of histones, also called histone code, and nucleosome remodeling (By similarity). Required to maintain non-distal tip cell (DTC) fate of somatic gonadal [...] | 0.996 |
nap-1 | spr-2 | D2096.8.1 | C27B7.1b.1 | Nucleosome Assembly Protein; Belongs to the nucleosome assembly protein (NAP) family. | Suppressor of presenilin-2; Potential corepressor protein, which may affect chromatin structure and/or transcription. May participate in the transcriptional repression of the presenilin protein hop-1. Belongs to the nucleosome assembly protein (NAP) family. | 0.732 |
nap-1 | unc-85 | D2096.8.1 | F10G7.3.1 | Nucleosome Assembly Protein; Belongs to the nucleosome assembly protein (NAP) family. | Probable histone chaperone asf-1; Histone chaperone that facilitates histone deposition and histone exchange and removal during nucleosome assembly and disassembly. | 0.456 |
nhx-4 | spr-2 | F14B8.1a.2 | C27B7.1b.1 | Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. | Suppressor of presenilin-2; Potential corepressor protein, which may affect chromatin structure and/or transcription. May participate in the transcriptional repression of the presenilin protein hop-1. Belongs to the nucleosome assembly protein (NAP) family. | 0.660 |
rba-1 | asfl-1 | K07A1.11.1 | C03D6.5.1 | Probable histone-binding protein rba-1; Core histone-binding subunit that may target chromatin assembly factors, chromatin remodeling factors and histone deacetylases to their histone substrates in a manner that is regulated by nucleosomal DNA (By similarity). Plays a role in regulating cell cycle progression. Required to repress the induction of vulval development by Ras signaling. In association with the zinc finger protein ztf-11, negatively regulates the expression of non- neuronal genes during neurogenesis. Belongs to the WD repeat RBAP46/RBAP48/MSI1 family. | Probable histone chaperone asf-1-like protein; Histone chaperone that facilitates histone deposition and histone exchange and removal during nucleosome assembly and disassembly. | 0.855 |
rba-1 | bub-3 | K07A1.11.1 | Y54G9A.6.1 | Probable histone-binding protein rba-1; Core histone-binding subunit that may target chromatin assembly factors, chromatin remodeling factors and histone deacetylases to their histone substrates in a manner that is regulated by nucleosomal DNA (By similarity). Plays a role in regulating cell cycle progression. Required to repress the induction of vulval development by Ras signaling. In association with the zinc finger protein ztf-11, negatively regulates the expression of non- neuronal genes during neurogenesis. Belongs to the WD repeat RBAP46/RBAP48/MSI1 family. | Mitotic checkpoint protein bub-3; Has a dual function in spindle-assembly checkpoint signaling and in promoting the establishment of correct kinetochore-microtubule (K-MT) attachments. Promotes the formation of stable end-on bipolar attachments of chromosomes. Necessary for expression and kinetochore localization of bub-1. Plays a role in synapsis checkpoint signaling inducing apoptosis in response to unsynapsed chromosomes and thus controlling chromosomal segregation during oocyte meiosis. | 0.551 |