STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pdl-1Phosphodiesterase delta-like protein. (159 aa)    
Predicted Functional Partners:
arl-3
ADP-ribosylation factor-like protein 3; GTP-binding protein that may be involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus.
   
 
 0.959
evl-20
ADP-ribosylation factor-like protein 2; GTP-binding protein that functions in embryogenesis, cytokinesis, germline development and microtubulule cytoskeleton dynamics.
    
 0.945
guk-1
Guanylate kinase-like domain-containing protein.
     
 0.923
acy-1
Adenylyl CYclase.
   
 
  0.907
F32D1.5
GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.
     
 0.902
F25B5.3
Putative cytosolic 5'-nucleotidase 3.
     
  0.900
gmps-1
Probable GMP synthase [glutamine-hydrolyzing].
     
  0.900
T19B4.3
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. Belongs to the purine/pyrimidine phosphoribosyltransferase family.
     
  0.900
hprt-1
Hypoxanthine phosphoribosyltransferase.
     
  0.900
Y10G11A.1
5'-nucleotidase; Belongs to the pyrimidine 5'-nucleotidase family.
     
  0.900
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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