STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
C27H6.9Mitochondrial genome maintenance exonuclease 1; Metal-dependent single-stranded DNA (ssDNA) exonuclease involved in mitochondrial genome maintenance; Belongs to the MGME1 family. (284 aa)    
Predicted Functional Partners:
T20G5.9
Mago-bind domain-containing protein.
   
  
 0.971
tofu-1
Twenty One u-rna (21U-RNA) biogenesis Fouled Up.
 
 
    0.598
srh-1
Serpentine Receptor, class H.
      
 0.531
rpap-3
RPAP3_C domain-containing protein.
   
    0.438
M05D6.2
Uncharacterized protein.
   
    0.418
him-18
High Incidence of Males (Increased X chromosome loss).
   
    0.414
zhp-3
RING-type domain-containing protein.
   
    0.412
gtf-2E2
Transcription initiation factor IIE subunit beta; Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase.
   
    0.410
sds-22
Protein phosphatase 1 regulatory subunit SDS22 homolog; Regulatory subunit of protein phosphatase 1; Belongs to the SDS22 family.
   
    0.410
ccch-3
C3H1-type domain-containing protein.
   
    0.406
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.