STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
wrt-8Warthog protein 8 C-product; Intercellular signal essential for a variety of patterning events during development. (550 aa)    
Predicted Functional Partners:
grl-16
Ground-like domain-containing protein.
   
  
 0.877
che-14
SSD domain-containing protein.
   
 
 0.712
wrt-3
Warthog protein 3; Intercellular signal essential for a variety of patterning events during development.
      
 0.680
ptd-2
SSD domain-containing protein.
    
 
 0.664
grd-9
Ground-like domain-containing protein.
      
 0.660
F40C5.1
Uncharacterized protein.
      
 0.660
grl-3
Ground-like domain-containing protein.
      
 0.637
vha-5
V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.
      
 0.614
wrt-10
WaRThog (Hedgehog-like family).
 
 
  
 0.607
clec-230
C-type lectin domain-containing protein.
   
    0.606
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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