STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
best-7Bestrophin homolog; Forms chloride channels; Belongs to the bestrophin family. (540 aa)    
Predicted Functional Partners:
C06B3.7
Uncharacterized protein.
      
 0.808
F10A3.17
FTH domain-containing protein.
      
 0.808
C35A5.3
MFS domain-containing protein.
   
  
 0.707
gst-27
Glutathione S-Transferase.
   
  
 0.689
sulp-5
STAS domain-containing protein.
   
  
 0.670
ugt-5
UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family.
   
  
 0.666
B0454.6
AA_permease_C domain-containing protein.
      
 0.664
C23H4.6
AAA_23 domain-containing protein.
      
 0.664
gst-2
Glutathione S-transferase 2; Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Belongs to the GST superfamily. Sigma family.
   
  
 0.663
ugt-10
UDP-GlucuronosylTransferase.
      
 0.663
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.