STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
C30B5.2Vacuolar protein sorting-associated protein 55 homolog; Involved in endosomal protein transport. (132 aa)    
Predicted Functional Partners:
Y74C10AL.2
Uncharacterized protein.
   
 
 0.979
apc-11
Anaphase-promoting complex subunit 11; Probable component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins. Developmental role in early embryogenesis and the metaphase to anaphase transition in meiosis and mitosis. In vitro, recruits the ubiquitin-conjugating enzyme ubc-2 to exert ubiquitin ligase activity. Belongs to the RING-box family.
      
 0.642
natc-2
N-acetyltransferase domain-containing protein.
   
 
 0.420
arl-8
Novel small G protein indispensable for equal chromosome segregation; Belongs to the small GTPase superfamily. Arf family.
   
    0.420
rps-30
40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family.
      
 0.414
tbc-3
Rab-GAP TBC domain-containing protein.
   
  
 0.407
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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