STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sdz-4SKN-1 Dependent Zygotic transcript. (345 aa)    
Predicted Functional Partners:
fbxb-41
F-box domain-containing protein.
   
    0.592
sdz-28
SKN-1 Dependent Zygotic transcript.
   
    0.592
T05D4.2
FBA_2 domain-containing protein.
   
    0.592
fbxc-18
F-box C protein.
   
   
0.560
Y71A12B.11
Uncharacterized protein.
   
    0.555
sdz-30
SKN-1 Dependent Zygotic transcript.
   
    0.545
sepa-1
Protein sepa-1; Adapter protein that connects P-granules in somatic cells with the autophagic machinery. Association with other adapters such as epg-2 and P-granule components such as pgl-3 is required for the accumulation and degradation of P-granules by autophagy in somatic cells. This ensures exclusive localization of the P-granules in germ cells.
   
    0.543
F14B6.3
Uncharacterized protein.
   
    0.542
sdz-9
SKN-1 Dependent Zygotic transcript.
   
    0.541
skr-9
SKp1 Related (Ubiquitin ligase complex component); Belongs to the SKP1 family.
   
    0.539
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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