STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
C32D5.123Beta_HSD domain-containing protein; Belongs to the 3-beta-HSD family. (357 aa)    
Predicted Functional Partners:
W08F4.3
Uncharacterized protein.
   
 
 0.949
hsd-2
3Beta_HSD domain-containing protein; Belongs to the 3-beta-HSD family.
      
 0.913
rps-30
40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family.
   
 
 0.895
F49E12.10
Fatty acid hydroxylase domain-containing protein; Belongs to the sterol desaturase family.
  
 0.885
dhcr-7
DeHydroCholesterol Reductase.
   
 
 0.878
erg-28
Probable ergosterol biosynthetic protein 28 homolog; Promotes the translocation of slo-1 potassium ion channels from the endoplasmic reticulum to its final destination at the plasma membrane, probably by shielding from premature proteasomal degradation in the endoplasmic reticulum; Belongs to the ERG28 family.
   
 
 0.866
cutl-28
CUTiclin-Like.
   
 
 0.864
rpl-15
60S ribosomal protein L15; Belongs to the eukaryotic ribosomal protein eL15 family.
   
 
 0.854
agmo-1
Alkylglycerol monooxygenase; Glyceryl-ether monooxygenase that cleaves the O-alkyl bond of ether lipids; Belongs to the sterol desaturase family. TMEM195 subfamily.
  
 0.851
F56A11.6
Uncharacterized protein.
      
 0.850
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.