STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
svh-5Uncharacterized protein. (493 aa)    
Predicted Functional Partners:
pkc-3
Protein kinase C-like 3; Required for the normal progression of embryogenesis and viability of the organism. Plays an indispensable role in establishing embryonic polarity and in recruiting and maintaining par-6 to the periphery, through interaction with par-3. Required for epithelial cell polarity in the distal spermatheca. Phosphorylates serine residues of num-1. Required for the expression of antimicrobial peptide nlp-29 in response in response to fungal infection or physical injury.
    
 0.773
T22C1.1
UBR-type domain-containing protein.
      
 0.700
F10D2.10
Uncharacterized protein.
      
 0.697
K01A12.4
Uncharacterized protein.
      
 0.697
F31E9.6
Uncharacterized protein.
      
 0.660
C50H11.8
Uncharacterized protein.
      
 0.531
svh-2
Tyrosine-protein kinase receptor svh-2; Receptor tyrosine kinase which may phosphorylate mlk-1, a component of the mlk-1, mek-1 and kgb-1 pathway. Involved in axon regeneration after injury by promoting the generation of productive and stable growth cones.
   
 
 0.530
ets-9
ETS domain-containing protein.
   
 
 0.504
rfip-1
FIP-RBD domain-containing protein.
   
  
 0.497
nhr-3
Nuclear hormone receptor family member nhr-3; Orphan nuclear receptor; Belongs to the nuclear hormone receptor family.
  
 
 0.493
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.