STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ethe-1Lactamase_B domain-containing protein. (237 aa)    
Predicted Functional Partners:
suox-1
Cytochrome b5 heme-binding domain-containing protein.
   
 
 0.993
sqrd-1
Pyr_redox_2 domain-containing protein.
  
 
 0.989
Y9C9A.16
Pyr_redox_2 domain-containing protein.
  
 
 0.955
mpst-1
Putative thiosulfate sulfurtransferase mpst-1.
  
 
 0.937
mpst-4
Thiosulfate/3-mercaptopyruvate sulfurtransferase.
  
 
 0.913
mpst-2
Sulfurtransferase.
  
 
 0.913
mpst-7
MercaptoPyruvate SulfurTransferase homolog.
  
  
 0.830
cysl-4
Cysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family.
   
  
 0.721
cysl-1
Cysteine synthase 1; Catalyzes the formation of cysteine and acetate from O- acetylserine and hydrogen sulfide. By metabolizing hydrogen sulfide produced by cysl-2-mediated cyanide assimilation, mediates resistance to P.aeruginosa infection. Mediates survival in high levels of hydrogen sulfide. By sequestering egl-9, which in turn promotes hif-1- mediated transcription, regulates behavioral responses to hypoxia ; Belongs to the cysteine synthase/cystathionine beta- synthase family.
   
  
 0.696
tmem-131
TMEM131_like domain-containing protein.
      
 0.660
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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