Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| H24K24.2 | ceh-30 | H24K24.2a.1 | C33D12.7.1 | Uncharacterized protein. | Homeobox protein ceh-30; Cell-type specific anti-apoptotic transcription factor required for the sexually dimorphic survival of the male-specific CEM (cephalic male) sensory neurons during sex determination. In hermaphrodites, the homologous cells undergo programmed cell death due to transcriptional repression of ceh-30 by tra-1, the terminal regulator in the sex determination pathway. | 0.553 |
| H24K24.2 | fbxb-77 | H24K24.2a.1 | Y17G9B.7a.1 | Uncharacterized protein. | FBA_2 domain-containing protein. | 0.857 |
| ced-9 | ceh-30 | T07C4.8.1 | C33D12.7.1 | Apoptosis regulator ced-9; Plays a major role in programmed cell death (PCD, apoptosis). egl-1 binds to and directly inhibits the activity of ced-9, releasing the cell death activator ced-4 from a ced-9/ced-4 containing protein complex and allowing ced-4 to activate the cell-killing caspase ced-3. During larval development, required for the elimination of transient presynaptic components downstream of egl-1 and upstream of ced-4 and ced-3 apoptotic pathway. | Homeobox protein ceh-30; Cell-type specific anti-apoptotic transcription factor required for the sexually dimorphic survival of the male-specific CEM (cephalic male) sensory neurons during sex determination. In hermaphrodites, the homologous cells undergo programmed cell death due to transcriptional repression of ceh-30 by tra-1, the terminal regulator in the sex determination pathway. | 0.670 |
| ced-9 | egl-1 | T07C4.8.1 | F23B12.9.1 | Apoptosis regulator ced-9; Plays a major role in programmed cell death (PCD, apoptosis). egl-1 binds to and directly inhibits the activity of ced-9, releasing the cell death activator ced-4 from a ced-9/ced-4 containing protein complex and allowing ced-4 to activate the cell-killing caspase ced-3. During larval development, required for the elimination of transient presynaptic components downstream of egl-1 and upstream of ced-4 and ced-3 apoptotic pathway. | Programmed cell death activator egl-1; Plays a major role in programmed cell death (PCD or apoptosis) by negatively regulating ced-9. Binds to and directly inhibits the activity of ced-9, releasing the cell death activator ced-4 from a ced- 9/ced-4 containing protein complex and allowing ced-4 to activate the cell-killing caspase ced-3. Required to activate programmed cell death in the sister cells of the serotonergic neurosecretory motor (NSM) neurons during embryogenesis. Required to activate programmed cell death in the sister cells of the M4 motor neuron and I1 pharyngeal neuron du [...] | 0.999 |
| ceh-14 | ceh-30 | F46C8.5.1 | C33D12.7.1 | Homeobox protein ceh-14; Confers thermosensory function to neurons. Required for correct AFD-mediated thermotaxis. | Homeobox protein ceh-30; Cell-type specific anti-apoptotic transcription factor required for the sexually dimorphic survival of the male-specific CEM (cephalic male) sensory neurons during sex determination. In hermaphrodites, the homologous cells undergo programmed cell death due to transcriptional repression of ceh-30 by tra-1, the terminal regulator in the sex determination pathway. | 0.628 |
| ceh-14 | mab-3 | F46C8.5.1 | Y53C12B.5a.1 | Homeobox protein ceh-14; Confers thermosensory function to neurons. Required for correct AFD-mediated thermotaxis. | Protein male abnormal 3; Transcription factor which binds the DNA motif 5'- [CGA][TCA][TA]ACAATGT[AT][TGA]C-3', probably as a monomer. Acts partially redundantly with the transcription factor dmd-3 to coordinate tail tip cell fusion and retraction and thereby regulate male tail tip morphogenesis. Promotes male-specific development of two tissues, the peripheral nervous system and the intestine. In the peripheral nervous system, directs differentiation of sensory ray neuroblasts into peripheral sense organs. In the intestine, causes repression of vitellogenin gene transcription. | 0.409 |
| ceh-14 | tra-1 | F46C8.5.1 | Y47D3A.6a.1 | Homeobox protein ceh-14; Confers thermosensory function to neurons. Required for correct AFD-mediated thermotaxis. | Sex-determining transformer protein 1; Plays a major role in controlling sexual phenotype. Terminal global regulator in a well-characterized cascade of sex-determining genes. Promotes female development. Interacts with tra-2 to promote spermatogenesis. Promotes spermatogenesis through the Tip60 HAT complex and by regulating the expression of genes, such as fog-3, required for male development (By similarity). Association with chromatin and at the fog-3 promoter requires wdr-5.1, and may also require wdr-5.2. With trr-1, activates the fog-3 gene to determine sperm/oocyte cell fate (By s [...] | 0.465 |
| ceh-30 | H24K24.2 | C33D12.7.1 | H24K24.2a.1 | Homeobox protein ceh-30; Cell-type specific anti-apoptotic transcription factor required for the sexually dimorphic survival of the male-specific CEM (cephalic male) sensory neurons during sex determination. In hermaphrodites, the homologous cells undergo programmed cell death due to transcriptional repression of ceh-30 by tra-1, the terminal regulator in the sex determination pathway. | Uncharacterized protein. | 0.553 |
| ceh-30 | ced-9 | C33D12.7.1 | T07C4.8.1 | Homeobox protein ceh-30; Cell-type specific anti-apoptotic transcription factor required for the sexually dimorphic survival of the male-specific CEM (cephalic male) sensory neurons during sex determination. In hermaphrodites, the homologous cells undergo programmed cell death due to transcriptional repression of ceh-30 by tra-1, the terminal regulator in the sex determination pathway. | Apoptosis regulator ced-9; Plays a major role in programmed cell death (PCD, apoptosis). egl-1 binds to and directly inhibits the activity of ced-9, releasing the cell death activator ced-4 from a ced-9/ced-4 containing protein complex and allowing ced-4 to activate the cell-killing caspase ced-3. During larval development, required for the elimination of transient presynaptic components downstream of egl-1 and upstream of ced-4 and ced-3 apoptotic pathway. | 0.670 |
| ceh-30 | ceh-14 | C33D12.7.1 | F46C8.5.1 | Homeobox protein ceh-30; Cell-type specific anti-apoptotic transcription factor required for the sexually dimorphic survival of the male-specific CEM (cephalic male) sensory neurons during sex determination. In hermaphrodites, the homologous cells undergo programmed cell death due to transcriptional repression of ceh-30 by tra-1, the terminal regulator in the sex determination pathway. | Homeobox protein ceh-14; Confers thermosensory function to neurons. Required for correct AFD-mediated thermotaxis. | 0.628 |
| ceh-30 | egl-1 | C33D12.7.1 | F23B12.9.1 | Homeobox protein ceh-30; Cell-type specific anti-apoptotic transcription factor required for the sexually dimorphic survival of the male-specific CEM (cephalic male) sensory neurons during sex determination. In hermaphrodites, the homologous cells undergo programmed cell death due to transcriptional repression of ceh-30 by tra-1, the terminal regulator in the sex determination pathway. | Programmed cell death activator egl-1; Plays a major role in programmed cell death (PCD or apoptosis) by negatively regulating ced-9. Binds to and directly inhibits the activity of ced-9, releasing the cell death activator ced-4 from a ced- 9/ced-4 containing protein complex and allowing ced-4 to activate the cell-killing caspase ced-3. Required to activate programmed cell death in the sister cells of the serotonergic neurosecretory motor (NSM) neurons during embryogenesis. Required to activate programmed cell death in the sister cells of the M4 motor neuron and I1 pharyngeal neuron du [...] | 0.770 |
| ceh-30 | fbxb-77 | C33D12.7.1 | Y17G9B.7a.1 | Homeobox protein ceh-30; Cell-type specific anti-apoptotic transcription factor required for the sexually dimorphic survival of the male-specific CEM (cephalic male) sensory neurons during sex determination. In hermaphrodites, the homologous cells undergo programmed cell death due to transcriptional repression of ceh-30 by tra-1, the terminal regulator in the sex determination pathway. | FBA_2 domain-containing protein. | 0.569 |
| ceh-30 | lin-11 | C33D12.7.1 | ZC247.3.1 | Homeobox protein ceh-30; Cell-type specific anti-apoptotic transcription factor required for the sexually dimorphic survival of the male-specific CEM (cephalic male) sensory neurons during sex determination. In hermaphrodites, the homologous cells undergo programmed cell death due to transcriptional repression of ceh-30 by tra-1, the terminal regulator in the sex determination pathway. | Protein lin-11; Probable transcription factor which is required for asymmetric division of vulval blast cells. Involved in olfactory plasticity probably by regulating the expression of transcription factor mbr-1 in RIF neurons. Plays a role in the chemorepulsive response toward ascaroside pheromones mediated by the ADL sensory neurons, probably by regulating E-box motif 5'-CANNTG-3' containing target genes in the ADL neurons. Plays a role in the differentiation of the ADL sensory neurons. | 0.589 |
| ceh-30 | lin-13 | C33D12.7.1 | C03B8.4.1 | Homeobox protein ceh-30; Cell-type specific anti-apoptotic transcription factor required for the sexually dimorphic survival of the male-specific CEM (cephalic male) sensory neurons during sex determination. In hermaphrodites, the homologous cells undergo programmed cell death due to transcriptional repression of ceh-30 by tra-1, the terminal regulator in the sex determination pathway. | Zinc finger protein lin-13; Involved in repression of vulval fate, possibly by a tumor suppressor protein Rb-mediated mechanism. | 0.669 |
| ceh-30 | mab-3 | C33D12.7.1 | Y53C12B.5a.1 | Homeobox protein ceh-30; Cell-type specific anti-apoptotic transcription factor required for the sexually dimorphic survival of the male-specific CEM (cephalic male) sensory neurons during sex determination. In hermaphrodites, the homologous cells undergo programmed cell death due to transcriptional repression of ceh-30 by tra-1, the terminal regulator in the sex determination pathway. | Protein male abnormal 3; Transcription factor which binds the DNA motif 5'- [CGA][TCA][TA]ACAATGT[AT][TGA]C-3', probably as a monomer. Acts partially redundantly with the transcription factor dmd-3 to coordinate tail tip cell fusion and retraction and thereby regulate male tail tip morphogenesis. Promotes male-specific development of two tissues, the peripheral nervous system and the intestine. In the peripheral nervous system, directs differentiation of sensory ray neuroblasts into peripheral sense organs. In the intestine, causes repression of vitellogenin gene transcription. | 0.732 |
| ceh-30 | tra-1 | C33D12.7.1 | Y47D3A.6a.1 | Homeobox protein ceh-30; Cell-type specific anti-apoptotic transcription factor required for the sexually dimorphic survival of the male-specific CEM (cephalic male) sensory neurons during sex determination. In hermaphrodites, the homologous cells undergo programmed cell death due to transcriptional repression of ceh-30 by tra-1, the terminal regulator in the sex determination pathway. | Sex-determining transformer protein 1; Plays a major role in controlling sexual phenotype. Terminal global regulator in a well-characterized cascade of sex-determining genes. Promotes female development. Interacts with tra-2 to promote spermatogenesis. Promotes spermatogenesis through the Tip60 HAT complex and by regulating the expression of genes, such as fog-3, required for male development (By similarity). Association with chromatin and at the fog-3 promoter requires wdr-5.1, and may also require wdr-5.2. With trr-1, activates the fog-3 gene to determine sperm/oocyte cell fate (By s [...] | 0.701 |
| ceh-30 | unc-37 | C33D12.7.1 | W02D3.9.2 | Homeobox protein ceh-30; Cell-type specific anti-apoptotic transcription factor required for the sexually dimorphic survival of the male-specific CEM (cephalic male) sensory neurons during sex determination. In hermaphrodites, the homologous cells undergo programmed cell death due to transcriptional repression of ceh-30 by tra-1, the terminal regulator in the sex determination pathway. | Transcription factor unc-37; Transcriptional corepressor that functions with the neural specificity gene unc-4 to govern motor neuron identity. May function with transcription factor mls-1 to promote uterine muscle specification and formation. | 0.733 |
| egl-1 | ced-9 | F23B12.9.1 | T07C4.8.1 | Programmed cell death activator egl-1; Plays a major role in programmed cell death (PCD or apoptosis) by negatively regulating ced-9. Binds to and directly inhibits the activity of ced-9, releasing the cell death activator ced-4 from a ced- 9/ced-4 containing protein complex and allowing ced-4 to activate the cell-killing caspase ced-3. Required to activate programmed cell death in the sister cells of the serotonergic neurosecretory motor (NSM) neurons during embryogenesis. Required to activate programmed cell death in the sister cells of the M4 motor neuron and I1 pharyngeal neuron du [...] | Apoptosis regulator ced-9; Plays a major role in programmed cell death (PCD, apoptosis). egl-1 binds to and directly inhibits the activity of ced-9, releasing the cell death activator ced-4 from a ced-9/ced-4 containing protein complex and allowing ced-4 to activate the cell-killing caspase ced-3. During larval development, required for the elimination of transient presynaptic components downstream of egl-1 and upstream of ced-4 and ced-3 apoptotic pathway. | 0.999 |
| egl-1 | ceh-30 | F23B12.9.1 | C33D12.7.1 | Programmed cell death activator egl-1; Plays a major role in programmed cell death (PCD or apoptosis) by negatively regulating ced-9. Binds to and directly inhibits the activity of ced-9, releasing the cell death activator ced-4 from a ced- 9/ced-4 containing protein complex and allowing ced-4 to activate the cell-killing caspase ced-3. Required to activate programmed cell death in the sister cells of the serotonergic neurosecretory motor (NSM) neurons during embryogenesis. Required to activate programmed cell death in the sister cells of the M4 motor neuron and I1 pharyngeal neuron du [...] | Homeobox protein ceh-30; Cell-type specific anti-apoptotic transcription factor required for the sexually dimorphic survival of the male-specific CEM (cephalic male) sensory neurons during sex determination. In hermaphrodites, the homologous cells undergo programmed cell death due to transcriptional repression of ceh-30 by tra-1, the terminal regulator in the sex determination pathway. | 0.770 |
| egl-1 | mab-3 | F23B12.9.1 | Y53C12B.5a.1 | Programmed cell death activator egl-1; Plays a major role in programmed cell death (PCD or apoptosis) by negatively regulating ced-9. Binds to and directly inhibits the activity of ced-9, releasing the cell death activator ced-4 from a ced- 9/ced-4 containing protein complex and allowing ced-4 to activate the cell-killing caspase ced-3. Required to activate programmed cell death in the sister cells of the serotonergic neurosecretory motor (NSM) neurons during embryogenesis. Required to activate programmed cell death in the sister cells of the M4 motor neuron and I1 pharyngeal neuron du [...] | Protein male abnormal 3; Transcription factor which binds the DNA motif 5'- [CGA][TCA][TA]ACAATGT[AT][TGA]C-3', probably as a monomer. Acts partially redundantly with the transcription factor dmd-3 to coordinate tail tip cell fusion and retraction and thereby regulate male tail tip morphogenesis. Promotes male-specific development of two tissues, the peripheral nervous system and the intestine. In the peripheral nervous system, directs differentiation of sensory ray neuroblasts into peripheral sense organs. In the intestine, causes repression of vitellogenin gene transcription. | 0.461 |
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