STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
C33H5.16Tyrosine-protein phosphatase. (341 aa)    
Predicted Functional Partners:
kin-26
Tyrosine-protein kinase.
   
   0.639
kin-5
Tyrosine-protein kinase.
   
   0.639
T27A3.5
Tyrosine-protein phosphatase.
  
   
0.630
F47B3.1
Tyrosine-protein phosphatase.
  
   
0.621
ZK484.7
Tyrosine-protein phosphatase.
  
   
0.620
T22C1.8
Tyrosine-protein phosphatase.
  
  
0.612
Y57G11A.2
Uncharacterized protein.
   
   0.605
gsp-3
Serine/threonine-protein phosphatase PP1-gamma; Probable phosphatase which plays a redundant role with gsp-4 in spermatogenesis by regulating sister chromatid segregation during meiosis. In addition, involved in sperm motility by controlling the dynamic disassembly of major sperm proteins (MSP) in the spermatozoan pseudopodium.
   
   0.603
wht-5
ABC transporter domain-containing protein.
   
    0.600
rnh-1.1
RNase H domain-containing protein.
   
    0.600
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.