STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
zgpa-1Zinc finger G-PAtch domain-containing protein homolog. (432 aa)    
Predicted Functional Partners:
dif-1
Protein dif-1; Seems to play a role in the maintenance of tissue differentiation in the developing embryo, but not for its initiation.
 
    
 0.877
nuaf-3
NADH:Ubiquinone oxidoreductase Assembly Factor.
   
  
 0.853
prp-3
Yeast PRP (Splicing factor) related.
   
   0.757
dnj-11
DNaJ domain (Prokaryotic heat shock protein).
   
  
 0.753
marc-6
RING-CH-type domain-containing protein.
   
  
 0.743
sup-37
SUPpressor.
      
 0.741
aph-1
Gamma-secretase subunit aph-1; Essential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral proteins such as Notch receptors (lin-12 or glp-1). It may represent a stabilizing cofactor for the presenilin homodimer that promotes the formation of a stable complex. Required for the localization of aph-2.
   
  
 0.706
hmbx-1
Homeobox domain-containing protein.
      
 0.699
somi-1
Suppressor of Overexpressed MIcro-RNA.
      
 0.699
nduf-6
Probable NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
   
  
 0.697
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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