STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mys-4Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (617 aa)    
Predicted Functional Partners:
ZK1127.3
Uncharacterized protein.
   
 
 0.836
ekl-4
Uncharacterized protein.
   
 
 0.835
C17E4.6
YL1_C domain-containing protein.
   
 
 0.814
mrg-1
MRG domain-containing protein.
   
 
 0.811
C16A11.4
SPK domain-containing protein.
   
 
 0.767
epc-1
Enhancer of PolyComb-like.
   
 
 0.741
zhit-1
HIT-type domain-containing protein.
   
 
 0.736
gfl-1
GAS41-Like.
   
 
 0.687
htz-1
Histone H2A.V; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post- translational modifications of histones, also called histone code, and nucleosome remodeling (By similarity). Required to maintain non-distal tip cell (DTC) fate of somatic gonadal [...]
   
 
 0.687
arp-6
Actin-like protein C08B11.6; Belongs to the actin family. ARP6 subfamily.
   
 
 0.671
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
Server load: low (20%) [HD]