STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dmd-11DM domain-containing protein. (114 aa)    
Predicted Functional Partners:
dmd-5
DM domain-containing protein.
    
 
 0.932
mab-23
Putative transcription factor MAB-23.
      
 0.850
dmd-10
DM domain-containing protein.
   
  
 0.811
dmd-4
DM domain-containing protein.
    
 
 0.792
dmd-9
DM domain-containing protein.
      
 0.696
dmd-6
DM domain-containing protein.
      
 0.537
dmd-7
DM domain-containing protein.
      
 0.468
tra-1
Sex-determining transformer protein 1; Plays a major role in controlling sexual phenotype. Terminal global regulator in a well-characterized cascade of sex-determining genes. Promotes female development. Interacts with tra-2 to promote spermatogenesis. Promotes spermatogenesis through the Tip60 HAT complex and by regulating the expression of genes, such as fog-3, required for male development (By similarity). Association with chromatin and at the fog-3 promoter requires wdr-5.1, and may also require wdr-5.2. With trr-1, activates the fog-3 gene to determine sperm/oocyte cell fate (By s [...]
      
 0.468
srg-13
Serpentine receptor class gamma-13.
      
 0.420
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.