STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
zip-5BZIP domain-containing protein. (216 aa)    
Predicted Functional Partners:
zip-10
Transcription factor zip-10; Transcription factor that regulates the expression of genes in response to changes in temperature. In particular, binds to the promoter region of genes such as asp-17 in response to severe cold to warm temperature transitions to promote gene expression. Promotes stress-induced death, particularly in older animals, following cold shock followed by warming and this may have evolved as a form of kin survival under thermal stress conditions, favoring the survival of younger animals.
   
  
 0.712
best-23
Bestrophin homolog; Forms chloride channels; Belongs to the bestrophin family.
   
  
 0.703
F21G4.1
Solute carrier organic anion transporter family member.
   
  
 0.700
F14F9.3
Uncharacterized protein.
      
 0.697
ZK177.8
Uncharacterized protein ZK177.8.
      
 0.696
jun-1
Transcription factor jun-1; Transcription factor that recognizes and binds to the AP-1 non-canonical enhancer heptamer motif 5'-TTAGTCA-3'. Required for ovulation. Controls plc-1 expression in the spermatheca to regulate spermathecal valve dilation.
   
   0.678
K03H1.5
Uncharacterized protein K03H1.5.
   
  
 0.631
C18H7.11
Uncharacterized protein.
   
  
 0.624
Y47G6A.5
Tyrosine-protein kinase.
   
  
 0.624
C18H9.1
Uncharacterized protein.
      
 0.612
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.