STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
C34D4.4Uncharacterized Golgi apparatus membrane protein-like protein C34D4.4. (205 aa)    
Predicted Functional Partners:
unc-51
Serine/threonine-protein kinase unc-51; Protein kinase important for axonal elongation and axonal guidance. Functions in the CAN axons to direct both anterior and posterior migrations. Phosphorylates both unc-14 and vab-8. Component of the unc-51/atg-13 complex that is probably recruited by lgg-1 to preautophagosomes and is required for autophagosome formation. Interaction with autophagy related proteins such as atg-13 links it to the autophagy machinery to in turn promote P-granule degradation in somatic cells. Plays a role in mitophagy during limited food availability. Regulates cell [...]
    
   0.916
nstp-2
Nucleotide Sugar TransPorter family.
   
  
 0.894
F56D5.2
Uncharacterized protein.
      
 0.891
C52B9.4
Uncharacterized protein.
   
  
 0.853
T07F12.4
Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.
    
   0.851
T28D9.1
Uncharacterized protein T28D9.1.
   
  
 0.814
Y25C1A.7
Yip1 domain-containing protein.
   
 
 0.805
F27D9.2
MFS domain-containing protein.
      
 0.804
soap-1
Sorting Of Apical Proteins.
      
 0.800
W02D9.2
Protein YIPF.
   
 
 0.788
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.