STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
C34F6.9USP domain-containing protein; Belongs to the peptidase C19 family. (1181 aa)    
Predicted Functional Partners:
klu-1
KLUmpfuss related.
   
 
 0.863
taf-10
Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors; Belongs to the TAF10 family.
    
 
 0.825
pcaf-1
P300/CBP Associated Factor homolog.
    
 
 0.823
ubq-2
Ubiquitin-60S ribosomal protein L40; [Ubiquitin]: exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-48-linked is invol [...]
    
   0.822
trr-1
Transcription-associated protein 1; Influences germ cell fate in hermaphrodites. Acts downstream of tra-2 and tra-3 and through the Tip60 histone acetyltransferase complex to regulate germ cell fate decisions (By similarity). Required for spermatogenesis and embryonic development (By similarity). Acts with tra-2 to promote expression of fog-3 and control male tail development (By similarity). Involved in the negative regulation of vulval development. Belongs to the PI3/PI4-kinase family. TRA1 subfamily.
   
 
 0.821
fkh-10
Fork-head domain-containing protein.
   
  
 0.814
taf-5
TAF (TBP-associated transcription factor) family.
   
 
 0.812
ada-2
SANT domain-containing protein.
   
 
 0.811
taf-9
TAF (TBP-associated transcription factor) family.
    
 
 0.793
taf-12
TFIID_20kDa domain-containing protein.
    
 
 0.792
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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