node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
cap-2 | maph-1.2 | M106.5.1 | F25D7.4.1 | F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. | Microtubule-Associated Protein Homolog. | 0.772 |
cap-2 | maph-1.3 | M106.5.1 | C36A4.5.1 | F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. | Microtubule-Associated Protein Homolog. | 0.772 |
dlg-1 | maph-1.2 | C25F6.2a.1 | F25D7.4.1 | Disks large homolog 1; Essential multidomain scaffolding protein required for normal development (Probable). Recruits channels, receptors and signaling molecules to discrete plasma membrane domains in polarized cells (By similarity). Required for proper embryonic elongation. Acts upstream of ajm-1 and becomes localized to apical junctions independently of ajm-1. With let-413, cooperatively regulates ajm-1 localization to apical junctions. Belongs to the MAGUK family. | Microtubule-Associated Protein Homolog. | 0.401 |
dlg-1 | maph-1.3 | C25F6.2a.1 | C36A4.5.1 | Disks large homolog 1; Essential multidomain scaffolding protein required for normal development (Probable). Recruits channels, receptors and signaling molecules to discrete plasma membrane domains in polarized cells (By similarity). Required for proper embryonic elongation. Acts upstream of ajm-1 and becomes localized to apical junctions independently of ajm-1. With let-413, cooperatively regulates ajm-1 localization to apical junctions. Belongs to the MAGUK family. | Microtubule-Associated Protein Homolog. | 0.401 |
klp-7 | maph-1.2 | K11D9.1a.1 | F25D7.4.1 | Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. | Microtubule-Associated Protein Homolog. | 0.440 |
klp-7 | maph-1.3 | K11D9.1a.1 | C36A4.5.1 | Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. | Microtubule-Associated Protein Homolog. | 0.510 |
klp-7 | plk-2 | K11D9.1a.1 | Y71F9B.7.1 | Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. | Serine/threonine-protein kinase plk-2; Serine/threonine-protein kinase which plays a role, during oogenesis, in chromosome pairing and synapsis, by facilitating the recruitment and attachment of meiotic chromosomes to the nuclear envelope during prophase. Regulates the formation of sun-1 patches along the nuclear envelope. Promotes meiotic nuclei apoptosis in response to chromosomal asynapsis. Plays a redundant role with plk-1 in the establishment of cell polarity downstream of mex-5 and mex-6 during the first embryonic cell divisions. Plays a role in nicotinic acetylcholine receptor- [...] | 0.521 |
lgg-2 | maph-1.2 | ZK593.6a.1 | F25D7.4.1 | Protein lgg-2; Ubiquitin-like modifier involved in the formation of autophagosomal vacuoles (autophagosomes). When lipidated mediates tethering between adjacent membranes and stimulates membrane fusion. Less effective at promoting membrane fusion than lgg-1. Acts upstream of the autophagy protein epg-5 in the aggrephagy pathway, which is the macroautophagic degradation of ubiquitinated protein aggregates, and preferentially interacts with autophagy proteins and substrates containing LIR motifs to mediate autophagosome formation and protein aggregate degradation. In particular binds to [...] | Microtubule-Associated Protein Homolog. | 0.449 |
lgg-2 | maph-1.3 | ZK593.6a.1 | C36A4.5.1 | Protein lgg-2; Ubiquitin-like modifier involved in the formation of autophagosomal vacuoles (autophagosomes). When lipidated mediates tethering between adjacent membranes and stimulates membrane fusion. Less effective at promoting membrane fusion than lgg-1. Acts upstream of the autophagy protein epg-5 in the aggrephagy pathway, which is the macroautophagic degradation of ubiquitinated protein aggregates, and preferentially interacts with autophagy proteins and substrates containing LIR motifs to mediate autophagosome formation and protein aggregate degradation. In particular binds to [...] | Microtubule-Associated Protein Homolog. | 0.449 |
maph-1.2 | cap-2 | F25D7.4.1 | M106.5.1 | Microtubule-Associated Protein Homolog. | F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. | 0.772 |
maph-1.2 | dlg-1 | F25D7.4.1 | C25F6.2a.1 | Microtubule-Associated Protein Homolog. | Disks large homolog 1; Essential multidomain scaffolding protein required for normal development (Probable). Recruits channels, receptors and signaling molecules to discrete plasma membrane domains in polarized cells (By similarity). Required for proper embryonic elongation. Acts upstream of ajm-1 and becomes localized to apical junctions independently of ajm-1. With let-413, cooperatively regulates ajm-1 localization to apical junctions. Belongs to the MAGUK family. | 0.401 |
maph-1.2 | klp-7 | F25D7.4.1 | K11D9.1a.1 | Microtubule-Associated Protein Homolog. | Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. | 0.440 |
maph-1.2 | lgg-2 | F25D7.4.1 | ZK593.6a.1 | Microtubule-Associated Protein Homolog. | Protein lgg-2; Ubiquitin-like modifier involved in the formation of autophagosomal vacuoles (autophagosomes). When lipidated mediates tethering between adjacent membranes and stimulates membrane fusion. Less effective at promoting membrane fusion than lgg-1. Acts upstream of the autophagy protein epg-5 in the aggrephagy pathway, which is the macroautophagic degradation of ubiquitinated protein aggregates, and preferentially interacts with autophagy proteins and substrates containing LIR motifs to mediate autophagosome formation and protein aggregate degradation. In particular binds to [...] | 0.449 |
maph-1.2 | maph-1.3 | F25D7.4.1 | C36A4.5.1 | Microtubule-Associated Protein Homolog. | Microtubule-Associated Protein Homolog. | 0.847 |
maph-1.2 | npp-9 | F25D7.4.1 | F59A2.1b.3 | Microtubule-Associated Protein Homolog. | Nuclear Pore complex Protein. | 0.500 |
maph-1.2 | plk-2 | F25D7.4.1 | Y71F9B.7.1 | Microtubule-Associated Protein Homolog. | Serine/threonine-protein kinase plk-2; Serine/threonine-protein kinase which plays a role, during oogenesis, in chromosome pairing and synapsis, by facilitating the recruitment and attachment of meiotic chromosomes to the nuclear envelope during prophase. Regulates the formation of sun-1 patches along the nuclear envelope. Promotes meiotic nuclei apoptosis in response to chromosomal asynapsis. Plays a redundant role with plk-1 in the establishment of cell polarity downstream of mex-5 and mex-6 during the first embryonic cell divisions. Plays a role in nicotinic acetylcholine receptor- [...] | 0.531 |
maph-1.2 | ptl-1 | F25D7.4.1 | F42G9.9b.1 | Microtubule-Associated Protein Homolog. | Microtubule-associated protein. | 0.427 |
maph-1.2 | rsf-1 | F25D7.4.1 | T24F1.3a.1 | Microtubule-Associated Protein Homolog. | RASSF (Ras-association domain family) homolog. | 0.417 |
maph-1.2 | sms-2 | F25D7.4.1 | F53H8.4.1 | Microtubule-Associated Protein Homolog. | Phosphatidylcholine:ceramide cholinephosphotransferase 2; Sphingomyelin synthases synthesize the sphingolipid, sphingomyelin, through transfer of the phosphatidyl head group, phosphatidylcholine, on to the primary hydroxyl of ceramide. The reaction is bidirectional depending on the respective levels of the sphingolipid and ceramide. | 0.808 |
maph-1.3 | cap-2 | C36A4.5.1 | M106.5.1 | Microtubule-Associated Protein Homolog. | F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. | 0.772 |