STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
acs-19Acetyl-coenzyme A synthetase. (680 aa)    
Predicted Functional Partners:
icl-1
Bifunctional glyoxylate cycle protein; In the C-terminal section; belongs to the malate synthase family.
  
 0.998
cts-1
Probable citrate synthase, mitochondrial.
  
 0.996
alh-1
Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family.
  
 0.981
alh-5
Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
  
 0.981
T02G5.7
Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.980
alh-4
Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
  
 0.979
acox-1.4
Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family.
  
 
 0.977
acox-3
Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family.
  
 
 0.977
alh-2
Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family.
  
 0.976
kat-1
Acetyl-CoA acetyltransferase homolog, mitochondrial; Plays a role in ketone body metabolism (By similarity). Has an effect on lysosome related organelles (LRO) function, in a pathway with serotonin. Acts downstream of sir-2.1 to regulate aging and stress resistance. Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.975
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.