Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| athp-2 | gls-1 | H20J04.2.1 | C36B1.8b.1 | AT Hook plus PHD finger transcription factor. | Germline survival defective-1; Required maternally for germline survival by forming a maternal complex with gld-3. During hermaphrodite development forms a complex with gld-3 which promotes the sperm/oocyte switch freeing the translational repressor fbf to turn off sperm promoting factors. Required for proper oocyte differentiation and oogenic meiotic arrest. Stimulates the enzymatic activity of gld-4 and together they prevent gld-1 mRNA degradation. | 0.538 |
| fbf-1 | gld-3 | H12I13.4.1 | T07F8.3a.1 | Fem-3 mRNA-binding factor 1; Involved in the control of stem cells and sex determination in the C.elegans hermaphrodite germline. May also play a role in the hermaphrodite germline proliferation and oogenesis. Binds specifically to the regulatory region of fem-3 3'-UTR and mediates the sperm/oocyte switch. Negatively regulates gld-3 expression, possibly by directly binding to two sites within the 3'-UTR of gld-3 isoform b. In association with the cye-1/cdk-2 complex, negatively regulates gld-1 expression in the distal germline cells of the mitotic zone. By binding to the 3'-UTR, repres [...] | Defective in germ line development protein 3; Required maternally for germline survival and embryogenesis. Forms a complex with gls-1 which promotes the oogenic cell fate by freeing the translational repressor fbf to repress sperm promoting factors. Promotes maturation of primary spermatocytes to mature sperm. Required during hermaphrodite development to promote sperm fate, which is critical for determining the normal number of sperm. Promotion of sperm fate is at the expense of oogenesis, possibly through the negative regulation of fbf. Required during male development for the continu [...] | 0.953 |
| fbf-1 | gls-1 | H12I13.4.1 | C36B1.8b.1 | Fem-3 mRNA-binding factor 1; Involved in the control of stem cells and sex determination in the C.elegans hermaphrodite germline. May also play a role in the hermaphrodite germline proliferation and oogenesis. Binds specifically to the regulatory region of fem-3 3'-UTR and mediates the sperm/oocyte switch. Negatively regulates gld-3 expression, possibly by directly binding to two sites within the 3'-UTR of gld-3 isoform b. In association with the cye-1/cdk-2 complex, negatively regulates gld-1 expression in the distal germline cells of the mitotic zone. By binding to the 3'-UTR, repres [...] | Germline survival defective-1; Required maternally for germline survival by forming a maternal complex with gld-3. During hermaphrodite development forms a complex with gld-3 which promotes the sperm/oocyte switch freeing the translational repressor fbf to turn off sperm promoting factors. Required for proper oocyte differentiation and oogenic meiotic arrest. Stimulates the enzymatic activity of gld-4 and together they prevent gld-1 mRNA degradation. | 0.542 |
| gld-3 | fbf-1 | T07F8.3a.1 | H12I13.4.1 | Defective in germ line development protein 3; Required maternally for germline survival and embryogenesis. Forms a complex with gls-1 which promotes the oogenic cell fate by freeing the translational repressor fbf to repress sperm promoting factors. Promotes maturation of primary spermatocytes to mature sperm. Required during hermaphrodite development to promote sperm fate, which is critical for determining the normal number of sperm. Promotion of sperm fate is at the expense of oogenesis, possibly through the negative regulation of fbf. Required during male development for the continu [...] | Fem-3 mRNA-binding factor 1; Involved in the control of stem cells and sex determination in the C.elegans hermaphrodite germline. May also play a role in the hermaphrodite germline proliferation and oogenesis. Binds specifically to the regulatory region of fem-3 3'-UTR and mediates the sperm/oocyte switch. Negatively regulates gld-3 expression, possibly by directly binding to two sites within the 3'-UTR of gld-3 isoform b. In association with the cye-1/cdk-2 complex, negatively regulates gld-1 expression in the distal germline cells of the mitotic zone. By binding to the 3'-UTR, repres [...] | 0.953 |
| gld-3 | gld-4 | T07F8.3a.1 | ZK858.1.1 | Defective in germ line development protein 3; Required maternally for germline survival and embryogenesis. Forms a complex with gls-1 which promotes the oogenic cell fate by freeing the translational repressor fbf to repress sperm promoting factors. Promotes maturation of primary spermatocytes to mature sperm. Required during hermaphrodite development to promote sperm fate, which is critical for determining the normal number of sperm. Promotion of sperm fate is at the expense of oogenesis, possibly through the negative regulation of fbf. Required during male development for the continu [...] | Poly(A) RNA polymerase gld-4; Cytoplasmic poly(A) RNA polymerase that adds successive AMP monomers to the 3'-end of specific RNAs, forming a poly(A) tail. The enzymatic activity is enhanced by its interaction with gls-1. Required, together with gld-2, for early meiotic progression in male and female germ cells and for gld-1 protein accumulation in the hermaphrodite germline. In the germline, forms a complex with gls-1 which directly binds to gld-1 mRNA and prevents its degradation. | 0.868 |
| gld-3 | gls-1 | T07F8.3a.1 | C36B1.8b.1 | Defective in germ line development protein 3; Required maternally for germline survival and embryogenesis. Forms a complex with gls-1 which promotes the oogenic cell fate by freeing the translational repressor fbf to repress sperm promoting factors. Promotes maturation of primary spermatocytes to mature sperm. Required during hermaphrodite development to promote sperm fate, which is critical for determining the normal number of sperm. Promotion of sperm fate is at the expense of oogenesis, possibly through the negative regulation of fbf. Required during male development for the continu [...] | Germline survival defective-1; Required maternally for germline survival by forming a maternal complex with gld-3. During hermaphrodite development forms a complex with gld-3 which promotes the sperm/oocyte switch freeing the translational repressor fbf to turn off sperm promoting factors. Required for proper oocyte differentiation and oogenic meiotic arrest. Stimulates the enzymatic activity of gld-4 and together they prevent gld-1 mRNA degradation. | 0.581 |
| gld-3 | nasp-2 | T07F8.3a.1 | C50B6.2.1 | Defective in germ line development protein 3; Required maternally for germline survival and embryogenesis. Forms a complex with gls-1 which promotes the oogenic cell fate by freeing the translational repressor fbf to repress sperm promoting factors. Promotes maturation of primary spermatocytes to mature sperm. Required during hermaphrodite development to promote sperm fate, which is critical for determining the normal number of sperm. Promotion of sperm fate is at the expense of oogenesis, possibly through the negative regulation of fbf. Required during male development for the continu [...] | SHNi-TPR domain-containing protein. | 0.460 |
| gld-4 | gld-3 | ZK858.1.1 | T07F8.3a.1 | Poly(A) RNA polymerase gld-4; Cytoplasmic poly(A) RNA polymerase that adds successive AMP monomers to the 3'-end of specific RNAs, forming a poly(A) tail. The enzymatic activity is enhanced by its interaction with gls-1. Required, together with gld-2, for early meiotic progression in male and female germ cells and for gld-1 protein accumulation in the hermaphrodite germline. In the germline, forms a complex with gls-1 which directly binds to gld-1 mRNA and prevents its degradation. | Defective in germ line development protein 3; Required maternally for germline survival and embryogenesis. Forms a complex with gls-1 which promotes the oogenic cell fate by freeing the translational repressor fbf to repress sperm promoting factors. Promotes maturation of primary spermatocytes to mature sperm. Required during hermaphrodite development to promote sperm fate, which is critical for determining the normal number of sperm. Promotion of sperm fate is at the expense of oogenesis, possibly through the negative regulation of fbf. Required during male development for the continu [...] | 0.868 |
| gld-4 | glna-2 | ZK858.1.1 | DH11.1a.2 | Poly(A) RNA polymerase gld-4; Cytoplasmic poly(A) RNA polymerase that adds successive AMP monomers to the 3'-end of specific RNAs, forming a poly(A) tail. The enzymatic activity is enhanced by its interaction with gls-1. Required, together with gld-2, for early meiotic progression in male and female germ cells and for gld-1 protein accumulation in the hermaphrodite germline. In the germline, forms a complex with gls-1 which directly binds to gld-1 mRNA and prevents its degradation. | Putative glutaminase 2. | 0.463 |
| gld-4 | gls-1 | ZK858.1.1 | C36B1.8b.1 | Poly(A) RNA polymerase gld-4; Cytoplasmic poly(A) RNA polymerase that adds successive AMP monomers to the 3'-end of specific RNAs, forming a poly(A) tail. The enzymatic activity is enhanced by its interaction with gls-1. Required, together with gld-2, for early meiotic progression in male and female germ cells and for gld-1 protein accumulation in the hermaphrodite germline. In the germline, forms a complex with gls-1 which directly binds to gld-1 mRNA and prevents its degradation. | Germline survival defective-1; Required maternally for germline survival by forming a maternal complex with gld-3. During hermaphrodite development forms a complex with gld-3 which promotes the sperm/oocyte switch freeing the translational repressor fbf to turn off sperm promoting factors. Required for proper oocyte differentiation and oogenic meiotic arrest. Stimulates the enzymatic activity of gld-4 and together they prevent gld-1 mRNA degradation. | 0.553 |
| gld-4 | ntl-9 | ZK858.1.1 | C26E6.3.1 | Poly(A) RNA polymerase gld-4; Cytoplasmic poly(A) RNA polymerase that adds successive AMP monomers to the 3'-end of specific RNAs, forming a poly(A) tail. The enzymatic activity is enhanced by its interaction with gls-1. Required, together with gld-2, for early meiotic progression in male and female germ cells and for gld-1 protein accumulation in the hermaphrodite germline. In the germline, forms a complex with gls-1 which directly binds to gld-1 mRNA and prevents its degradation. | NOT-Like (Yeast CCR4/NOT complex component). | 0.854 |
| glna-1 | glna-2 | C09F9.3f.1 | DH11.1a.2 | ANK_REP_REGION domain-containing protein. | Putative glutaminase 2. | 0.909 |
| glna-1 | gls-1 | C09F9.3f.1 | C36B1.8b.1 | ANK_REP_REGION domain-containing protein. | Germline survival defective-1; Required maternally for germline survival by forming a maternal complex with gld-3. During hermaphrodite development forms a complex with gld-3 which promotes the sperm/oocyte switch freeing the translational repressor fbf to turn off sperm promoting factors. Required for proper oocyte differentiation and oogenic meiotic arrest. Stimulates the enzymatic activity of gld-4 and together they prevent gld-1 mRNA degradation. | 0.581 |
| glna-2 | gld-4 | DH11.1a.2 | ZK858.1.1 | Putative glutaminase 2. | Poly(A) RNA polymerase gld-4; Cytoplasmic poly(A) RNA polymerase that adds successive AMP monomers to the 3'-end of specific RNAs, forming a poly(A) tail. The enzymatic activity is enhanced by its interaction with gls-1. Required, together with gld-2, for early meiotic progression in male and female germ cells and for gld-1 protein accumulation in the hermaphrodite germline. In the germline, forms a complex with gls-1 which directly binds to gld-1 mRNA and prevents its degradation. | 0.463 |
| glna-2 | glna-1 | DH11.1a.2 | C09F9.3f.1 | Putative glutaminase 2. | ANK_REP_REGION domain-containing protein. | 0.909 |
| glna-2 | gls-1 | DH11.1a.2 | C36B1.8b.1 | Putative glutaminase 2. | Germline survival defective-1; Required maternally for germline survival by forming a maternal complex with gld-3. During hermaphrodite development forms a complex with gld-3 which promotes the sperm/oocyte switch freeing the translational repressor fbf to turn off sperm promoting factors. Required for proper oocyte differentiation and oogenic meiotic arrest. Stimulates the enzymatic activity of gld-4 and together they prevent gld-1 mRNA degradation. | 0.612 |
| gls-1 | athp-2 | C36B1.8b.1 | H20J04.2.1 | Germline survival defective-1; Required maternally for germline survival by forming a maternal complex with gld-3. During hermaphrodite development forms a complex with gld-3 which promotes the sperm/oocyte switch freeing the translational repressor fbf to turn off sperm promoting factors. Required for proper oocyte differentiation and oogenic meiotic arrest. Stimulates the enzymatic activity of gld-4 and together they prevent gld-1 mRNA degradation. | AT Hook plus PHD finger transcription factor. | 0.538 |
| gls-1 | fbf-1 | C36B1.8b.1 | H12I13.4.1 | Germline survival defective-1; Required maternally for germline survival by forming a maternal complex with gld-3. During hermaphrodite development forms a complex with gld-3 which promotes the sperm/oocyte switch freeing the translational repressor fbf to turn off sperm promoting factors. Required for proper oocyte differentiation and oogenic meiotic arrest. Stimulates the enzymatic activity of gld-4 and together they prevent gld-1 mRNA degradation. | Fem-3 mRNA-binding factor 1; Involved in the control of stem cells and sex determination in the C.elegans hermaphrodite germline. May also play a role in the hermaphrodite germline proliferation and oogenesis. Binds specifically to the regulatory region of fem-3 3'-UTR and mediates the sperm/oocyte switch. Negatively regulates gld-3 expression, possibly by directly binding to two sites within the 3'-UTR of gld-3 isoform b. In association with the cye-1/cdk-2 complex, negatively regulates gld-1 expression in the distal germline cells of the mitotic zone. By binding to the 3'-UTR, repres [...] | 0.542 |
| gls-1 | gld-3 | C36B1.8b.1 | T07F8.3a.1 | Germline survival defective-1; Required maternally for germline survival by forming a maternal complex with gld-3. During hermaphrodite development forms a complex with gld-3 which promotes the sperm/oocyte switch freeing the translational repressor fbf to turn off sperm promoting factors. Required for proper oocyte differentiation and oogenic meiotic arrest. Stimulates the enzymatic activity of gld-4 and together they prevent gld-1 mRNA degradation. | Defective in germ line development protein 3; Required maternally for germline survival and embryogenesis. Forms a complex with gls-1 which promotes the oogenic cell fate by freeing the translational repressor fbf to repress sperm promoting factors. Promotes maturation of primary spermatocytes to mature sperm. Required during hermaphrodite development to promote sperm fate, which is critical for determining the normal number of sperm. Promotion of sperm fate is at the expense of oogenesis, possibly through the negative regulation of fbf. Required during male development for the continu [...] | 0.581 |
| gls-1 | gld-4 | C36B1.8b.1 | ZK858.1.1 | Germline survival defective-1; Required maternally for germline survival by forming a maternal complex with gld-3. During hermaphrodite development forms a complex with gld-3 which promotes the sperm/oocyte switch freeing the translational repressor fbf to turn off sperm promoting factors. Required for proper oocyte differentiation and oogenic meiotic arrest. Stimulates the enzymatic activity of gld-4 and together they prevent gld-1 mRNA degradation. | Poly(A) RNA polymerase gld-4; Cytoplasmic poly(A) RNA polymerase that adds successive AMP monomers to the 3'-end of specific RNAs, forming a poly(A) tail. The enzymatic activity is enhanced by its interaction with gls-1. Required, together with gld-2, for early meiotic progression in male and female germ cells and for gld-1 protein accumulation in the hermaphrodite germline. In the germline, forms a complex with gls-1 which directly binds to gld-1 mRNA and prevents its degradation. | 0.553 |
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