node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
aho-3 | gcy-28 | K04G2.2.1 | T01A4.1c.1 | Alpha/beta hydrolase domain-containing protein aho-3; Hydrolyzes fatty acids from S-acylated cysteine residues in proteins (By similarity). Acts in sensory neurons including AWC to regulate starvation-induced thermotaxis plasticity and salt learning behavior; Belongs to the AB hydrolase superfamily. ABHD17 family. | Receptor-type guanylate cyclase gcy-28; Guanylate cyclase involved in the production of the second messenger cGMP. Regulates olfactory perception in AWC sensory neurons although may not be involved in the primary sensory transduction steps. [Isoform d]: Regulates sensory integration of conflicting sensory cues in AIA interneurons. | 0.660 |
aho-3 | hen-1 | K04G2.2.1 | C36B7.7.1 | Alpha/beta hydrolase domain-containing protein aho-3; Hydrolyzes fatty acids from S-acylated cysteine residues in proteins (By similarity). Acts in sensory neurons including AWC to regulate starvation-induced thermotaxis plasticity and salt learning behavior; Belongs to the AB hydrolase superfamily. ABHD17 family. | HEsitatioN behavior. | 0.669 |
casy-1 | hen-1 | B0034.3a.1 | C36B7.7.1 | CAlSYntenin/Alcadein homolog. | HEsitatioN behavior. | 0.668 |
casy-1 | srab-6 | B0034.3a.1 | C36C5.10.1 | CAlSYntenin/Alcadein homolog. | Serpentine Receptor, class AB (Class A-like). | 0.660 |
fkb-8 | hen-1 | Y18D10A.25.1 | C36B7.7.1 | Peptidylprolyl isomerase. | HEsitatioN behavior. | 0.663 |
fkb-8 | henn-1 | Y18D10A.25.1 | C02F5.6b.1 | Peptidylprolyl isomerase. | Small RNA 2'-O-methyltransferase; Methyltransferase that adds a 2'-O-methyl group at the 3'-end of PIWI-interacting RNAs (piRNAs) and small interfering RNAs (siRNAs) which are classes of regulatory RNAs that are involved in gene silencing in endogenous RNA interference (RNAi) pathways. Methylation protects the 3'-end of small RNAs from tailing and trimming and could constitute a recognition signal for appropriate argonaute machineries (Probable). Methylates and stabilizes 26G-siRNAs (a class of 26 nucleotide siRNAs that possess a monophosphorylated guanine residue at the 5'-end) when t [...] | 0.681 |
gcy-28 | aho-3 | T01A4.1c.1 | K04G2.2.1 | Receptor-type guanylate cyclase gcy-28; Guanylate cyclase involved in the production of the second messenger cGMP. Regulates olfactory perception in AWC sensory neurons although may not be involved in the primary sensory transduction steps. [Isoform d]: Regulates sensory integration of conflicting sensory cues in AIA interneurons. | Alpha/beta hydrolase domain-containing protein aho-3; Hydrolyzes fatty acids from S-acylated cysteine residues in proteins (By similarity). Acts in sensory neurons including AWC to regulate starvation-induced thermotaxis plasticity and salt learning behavior; Belongs to the AB hydrolase superfamily. ABHD17 family. | 0.660 |
gcy-28 | hen-1 | T01A4.1c.1 | C36B7.7.1 | Receptor-type guanylate cyclase gcy-28; Guanylate cyclase involved in the production of the second messenger cGMP. Regulates olfactory perception in AWC sensory neurons although may not be involved in the primary sensory transduction steps. [Isoform d]: Regulates sensory integration of conflicting sensory cues in AIA interneurons. | HEsitatioN behavior. | 0.549 |
gcy-28 | scd-2 | T01A4.1c.1 | T10H9.2.1 | Receptor-type guanylate cyclase gcy-28; Guanylate cyclase involved in the production of the second messenger cGMP. Regulates olfactory perception in AWC sensory neurons although may not be involved in the primary sensory transduction steps. [Isoform d]: Regulates sensory integration of conflicting sensory cues in AIA interneurons. | ALK tyrosine kinase receptor homolog scd-2; Probable tyrosine-protein kinase receptor which regulates the dauer/non-dauer developmental decision probably by controlling daf-3 transcriptional activity in parallel or together with the TGF-beta pathway. Regulates integration of conflicting sensory cues in AIA interneurons. May act as a receptor for hen-1. | 0.555 |
gcy-28 | ttx-3 | T01A4.1c.1 | C40H5.5a.1 | Receptor-type guanylate cyclase gcy-28; Guanylate cyclase involved in the production of the second messenger cGMP. Regulates olfactory perception in AWC sensory neurons although may not be involved in the primary sensory transduction steps. [Isoform d]: Regulates sensory integration of conflicting sensory cues in AIA interneurons. | LIM/homeobox protein ttx-3; Required for specification of the AIA and AIY interneurons and the NSM neurons. Positively regulates the expression of a number of genes including ceh-23, kal-1, hen-1, ser-2, unc-17 and sra-11 in AIY interneurons and cat-4, flp-4, bas-1, ptps-1 and mgl-1 in NSM neurons. Also acts in an autoregulatory feedback loop to maintain its own expression. Plays a role in the thermotactic response, olfactory imprinting, regulation of longevity, control of dauer formation and axon outgrowth and pathfinding. Not required for normal chemosensory behavior. | 0.660 |
hen-1 | aho-3 | C36B7.7.1 | K04G2.2.1 | HEsitatioN behavior. | Alpha/beta hydrolase domain-containing protein aho-3; Hydrolyzes fatty acids from S-acylated cysteine residues in proteins (By similarity). Acts in sensory neurons including AWC to regulate starvation-induced thermotaxis plasticity and salt learning behavior; Belongs to the AB hydrolase superfamily. ABHD17 family. | 0.669 |
hen-1 | casy-1 | C36B7.7.1 | B0034.3a.1 | HEsitatioN behavior. | CAlSYntenin/Alcadein homolog. | 0.668 |
hen-1 | fkb-8 | C36B7.7.1 | Y18D10A.25.1 | HEsitatioN behavior. | Peptidylprolyl isomerase. | 0.663 |
hen-1 | gcy-28 | C36B7.7.1 | T01A4.1c.1 | HEsitatioN behavior. | Receptor-type guanylate cyclase gcy-28; Guanylate cyclase involved in the production of the second messenger cGMP. Regulates olfactory perception in AWC sensory neurons although may not be involved in the primary sensory transduction steps. [Isoform d]: Regulates sensory integration of conflicting sensory cues in AIA interneurons. | 0.549 |
hen-1 | henn-1 | C36B7.7.1 | C02F5.6b.1 | HEsitatioN behavior. | Small RNA 2'-O-methyltransferase; Methyltransferase that adds a 2'-O-methyl group at the 3'-end of PIWI-interacting RNAs (piRNAs) and small interfering RNAs (siRNAs) which are classes of regulatory RNAs that are involved in gene silencing in endogenous RNA interference (RNAi) pathways. Methylation protects the 3'-end of small RNAs from tailing and trimming and could constitute a recognition signal for appropriate argonaute machineries (Probable). Methylates and stabilizes 26G-siRNAs (a class of 26 nucleotide siRNAs that possess a monophosphorylated guanine residue at the 5'-end) when t [...] | 0.708 |
hen-1 | scd-1 | C36B7.7.1 | H20J18.1a.1 | HEsitatioN behavior. | Suppressor of Constitutive Dauer formation. | 0.663 |
hen-1 | scd-2 | C36B7.7.1 | T10H9.2.1 | HEsitatioN behavior. | ALK tyrosine kinase receptor homolog scd-2; Probable tyrosine-protein kinase receptor which regulates the dauer/non-dauer developmental decision probably by controlling daf-3 transcriptional activity in parallel or together with the TGF-beta pathway. Regulates integration of conflicting sensory cues in AIA interneurons. May act as a receptor for hen-1. | 0.906 |
hen-1 | soc-1 | C36B7.7.1 | F41F3.2.1 | HEsitatioN behavior. | Multisubstrate adapter protein soc-1; Adapter protein which modulates signaling mediated by several receptor tyrosine kinases. Plays a role in fluid homeostasis, probably downstream of receptor egl-15 and upstream of let-60/Ras. Involved in nicotinic acetylcholine receptor (nAChR)-mediated sensitivity to nicotine and levamisole and gamma- aminobutyric acid (GABA)receptor-mediated sensitivity to muscimol. Regulates synaptic levels of nAchR receptor subunit lev-1 and unc-38, and GABA receptor subunit unc-49 in the nerve cord, probably downstream of egl-15. Regulates motility. During the [...] | 0.532 |
hen-1 | srab-6 | C36B7.7.1 | C36C5.10.1 | HEsitatioN behavior. | Serpentine Receptor, class AB (Class A-like). | 0.697 |
hen-1 | ttx-3 | C36B7.7.1 | C40H5.5a.1 | HEsitatioN behavior. | LIM/homeobox protein ttx-3; Required for specification of the AIA and AIY interneurons and the NSM neurons. Positively regulates the expression of a number of genes including ceh-23, kal-1, hen-1, ser-2, unc-17 and sra-11 in AIY interneurons and cat-4, flp-4, bas-1, ptps-1 and mgl-1 in NSM neurons. Also acts in an autoregulatory feedback loop to maintain its own expression. Plays a role in the thermotactic response, olfactory imprinting, regulation of longevity, control of dauer formation and axon outgrowth and pathfinding. Not required for normal chemosensory behavior. | 0.660 |