STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
srab-6Serpentine Receptor, class AB (Class A-like). (330 aa)    
Predicted Functional Partners:
grd-12
Ground-like domain-containing protein.
      
 0.807
che-12
Crescerin-like protein che-12; Required for normal structure and function of sensory cilia on amphid neurons, especially for the formation of distal ciliary structures, but is less important for normal assembly of middle and basal ciliary structures. Plays a role in the organization of axoneme microtubule bundles in sensory cilia. Required for normal structure and function of the ASER neuron that mediates attraction to NaCl. Required for normal chemotaxis to NaCl. Required for normal avoidance response to high osmolarity. In contrast, is not required for normal chemotaxis to isoamyl al [...]
      
 0.759
hen-1
HEsitatioN behavior.
      
 0.697
casy-1
CAlSYntenin/Alcadein homolog.
      
 0.660
gcst-1
Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family.
  
 0.605
pdpr-1
Pyruvate Dehydrogenase Phosphatase Regulatory subunit.
  
 0.605
Y37E3.17
Uncharacterized protein.
  
 0.605
C26D10.3
Uncharacterized protein.
  
 0.540
sqrd-1
Pyr_redox_2 domain-containing protein.
  
 0.540
F20D6.11
Rieske domain-containing protein.
  
 0.540
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.