STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
inx-6Innexin-6; Structural component of the gap junctions. Belongs to the pannexin family. (389 aa)    
Predicted Functional Partners:
inx-7
Innexin-7; Structural component of the gap junctions. Belongs to the pannexin family.
  
   
0.612
gly-6
Probable N-acetylgalactosaminyltransferase 6; Probable glycopeptide transferase involved in O-linked oligosaccharide biosynthesis. Glycopeptide transferases catalyze the transfer of an N-acetyl-D-galactosamine residue to an already glycosylated peptide (By similarity). In contrast to other members of the family, it does not act as a peptide transferase that transfers GalNAc onto serine or threonine residue on peptides that have been tested. Some peptide transferase activity is however not excluded, considering that its appropriate peptide substrate may remain unidentified.
   
  
 0.582
dmsr-4
G_PROTEIN_RECEP_F1_2 domain-containing protein.
  
     0.492
unc-1
Protein unc-1.
   
  
 0.476
syx-3
Putative syntaxin-3; Potentially involved in docking of synaptic vesicles at presynaptic active zones (By similarity). Acts in the intestine to regulate anterior body muscle contractions (aBOC) and the expulsion steps during the defecation motor program (DMP).
    
 
 0.465
dmsr-5
G_PROTEIN_RECEP_F1_2 domain-containing protein.
  
    0.463
frpr-13
G_PROTEIN_RECEP_F1_2 domain-containing protein.
  
     0.457
inx-22
Innexin; Structural component of the gap junctions. Belongs to the pannexin family.
  
   
0.453
inx-14
Innexin-14; Structural component of the gap junctions.
  
   
0.441
nhl-2
NHL (Ring finger b-box coiled coil) domain containing.
  
     0.428
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.