STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
idhb-1Probable isocitrate dehydrogenase [NAD] subunit beta, mitochondrial; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (379 aa)    
Predicted Functional Partners:
idha-1
Probable isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial; Belongs to the isocitrate and isopropylmalate dehydrogenases family.
  
0.999
aco-2
Probable aconitate hydratase, mitochondrial; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate.
  
 0.992
idh-1
Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family.
  
 0.984
aco-1
Probable cytoplasmic aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate.
  
 0.982
idh-2
Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family.
  
 0.978
ogdh-1
2-oxoglutarate dehydrogenase, mitochondrial; The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components: 2-oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3) (By similarity).
  
 0.974
W07E11.1
Glutamine amidotransferase type-2 domain-containing protein.
  
 
 0.955
idhg-1
Isocitrate dehydrogenase [NAD] subunit, mitochondrial.
  
 
0.944
idhg-2
Isocitrate dehydrogenase [NAD] subunit, mitochondrial.
  
 
0.943
Y71G12B.10
Pyruvate carboxyltransferase domain-containing protein.
  
 0.930
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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