STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nex-4AnNEXin family. (404 aa)    
Predicted Functional Partners:
apl-1
Amyloid-beta-like protein; Required for normal developmental progression throughout all life stages. Specifically required for the molt stage during all larval transitions and morphogenesis. Acts with heterochronic genes, including members of the let-7 family, to regulate larval stage to adult transition. Acts synergistically with acn-1 in let-7 regulated postembryonic cell division of hypodermal seam cells. Acts in multiple pathways to influence daf-12 and daf-16 activity to in turn regulate physiological and reproductive processes such as body size and egg- laying. May play a role in [...]
   
 
 0.829
K01A2.10
Uncharacterized protein.
   
  
 0.701
T06G6.3
Uncharacterized protein.
   
  
 0.701
B0379.1
Uncharacterized protein.
      
 0.694
F37A4.6
Uncharacterized protein F37A4.6.
   
  
 0.694
R10E8.8
F-box domain-containing protein.
      
 0.694
Y53G8AL.1
FHA domain-containing protein.
      
 0.694
Y95B8A.6
Uncharacterized protein.
      
 0.692
fer-1
Sperm vesicle fusion protein fer-1; Required for the fusion of the membranous organelles (MOs) with the plasma membrane, a process essential in spermiogenesis.
   
 
 0.678
ttr-30
TransThyretin-Related family domain.
   
 
 0.571
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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