STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
C37H5.5Nucleolar complex protein 3 homolog. (778 aa)    
Predicted Functional Partners:
pro-2
Nucleolar complex protein 2 homolog; Required for normal somatic gonad development and for regulation of germline development and proliferation.
   
 
 0.999
nifk-1
RRM domain-containing protein.
   
 
 0.997
K12H4.3
Ribosome biogenesis protein BRX1 homolog; Required for biogenesis of the 60S ribosomal subunit. Belongs to the BRX1 family.
   
 
 0.995
nog-1
Nucleolar GTP-binding protein 1; Involved in the biogenesis of the 60S ribosomal subunit (By similarity). Has a role in regulating longevity, growth and brood size. May regulate fat storage via the insulin/IGF pathway.
   
 
 0.993
Y48B6A.1
Ribosome biogenesis protein BOP1 homolog; Required for maturation of ribosomal RNAs and formation of the large ribosomal subunit; Belongs to the WD repeat BOP1/ERB1 family.
   
 
 0.993
nst-1
Guanine nucleotide-binding protein-like 3 homolog; May play a role in regulating cellular proliferation in both germline and somatic tissues.
   
 
 0.992
nol-2
SAM_MT_RSMB_NOP domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
   
 
 0.992
C16A3.6
Protein MAK16 homolog; Belongs to the MAK16 family.
   
 
 0.989
F53F4.11
Uncharacterized protein.
   
 
 0.987
wdr-12
Ribosome biogenesis protein WDR12 homolog; Required for maturation of ribosomal RNAs and formation of the large ribosomal subunit; Belongs to the WD repeat WDR12/YTM1 family.
   
 
 0.983
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.