STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nas-9Zinc metalloproteinase nas-9; Metalloprotease. (546 aa)    
Predicted Functional Partners:
F42A10.6
Uncharacterized protein.
   
  
 0.817
F17A9.5
Oxidored_FMN domain-containing protein.
   
  
 0.748
nas-21
Zinc metalloproteinase-like protein nas-21; May lack metalloprotease activity.
  
   
 0.709
Y54E10BR.5
Signal peptidase complex catalytic subunit SEC11.
      
 0.697
F09C8.1
Lipase_GDSL domain-containing protein.
      
 0.667
clec-4
C-type LECtin.
      
 0.538
nas-19
Zinc metalloproteinase nas-19; Metalloprotease.
  
   
 0.531
adt-2
A disintegrin and metalloproteinase with thrombospondin motifs adt-2; Regulates body size probably independently of the TGF beta- like dbl-1 pathway. However, may regulate some dbl-1-mediated transcription. Plays a role in cuticle collagen fibril organization. Required for embryonic development.
   
  
 0.495
lec-6
Galectin.
   
  
 0.492
hch-1
Zinc metalloproteinase nas-34; Metalloprotease (By similarity). Required for normal hatching and migration of neuroblasts. May act by degrading eggshell proteins at hatching.
  
   
0.484
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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