node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
dbl-1 | gpn-1 | T25F10.2.1 | F59D12.4.1 | TGF_BETA_2 domain-containing protein. | GlyPicaN; Belongs to the glypican family. | 0.818 |
dbl-1 | lon-1 | T25F10.2.1 | F48E8.1a.1 | TGF_BETA_2 domain-containing protein. | Protein lon-1; Regulates body size morphogenesis, but does not affect male tail development; Belongs to the CRISP family. | 0.813 |
dbl-1 | lon-2 | T25F10.2.1 | C39E6.1.1 | TGF_BETA_2 domain-containing protein. | LONg; Belongs to the glypican family. | 0.810 |
dbl-1 | sdn-1 | T25F10.2.1 | F57C7.3a.1 | TGF_BETA_2 domain-containing protein. | Probable syndecan; Cell surface proteoglycan that bears heparan sulfate (By similarity). Required for correct mitotic spindle orientation of the ABar blastomere division plane and this may be through modulation of astral microtubule array, and in association with the wnt-signaling proteins mig-5 and dsh-2. Involved in the migration of AQR and PQR neurons, which descend from the Q neuroblasts. Promotes the axon guidance of D-type motor neurons. | 0.441 |
dbl-1 | sma-6 | T25F10.2.1 | C32D5.2.1 | TGF_BETA_2 domain-containing protein. | Serine/threonine-protein kinase sma-6; Involved in TGF-beta pathway. May be a receptor for daf-7; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. | 0.999 |
gpn-1 | dbl-1 | F59D12.4.1 | T25F10.2.1 | GlyPicaN; Belongs to the glypican family. | TGF_BETA_2 domain-containing protein. | 0.818 |
gpn-1 | hse-5 | F59D12.4.1 | B0285.5.1 | GlyPicaN; Belongs to the glypican family. | D-glucuronyl C5-epimerase; Converts D-glucuronic acid residues adjacent to N-sulfate sugar residues to L-iduronic acids (By similarity). Plays a role in the early migration of AQR and PQR neurons, which descend from the Q neuroblasts ; Belongs to the D-glucuronyl C5-epimerase family. | 0.901 |
gpn-1 | hst-2 | F59D12.4.1 | C34F6.4.1 | GlyPicaN; Belongs to the glypican family. | Heparan sulfate 2-O-sulfotransferase hst-2; Catalyzes the transfer of sulfate to the C2-position of selected hexuronic acid residues within the maturing heparan sulfate (HS). Involved in cell adhesion and guidance by specifically modifying proteoglycans in the extracellular matrix and on the cell surface that are essential for axon migrations. | 0.870 |
gpn-1 | hst-3.1 | F59D12.4.1 | F40H3.5.1 | GlyPicaN; Belongs to the glypican family. | Sulfotransfer_1 domain-containing protein. | 0.846 |
gpn-1 | hst-3.2 | F59D12.4.1 | F52B10.2.1 | GlyPicaN; Belongs to the glypican family. | Sulfotransfer_1 domain-containing protein. | 0.889 |
gpn-1 | hst-6 | F59D12.4.1 | Y34B4A.3.1 | GlyPicaN; Belongs to the glypican family. | Heparan-sulfate 6-O-sulfotransferase; 6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparan sulfate. | 0.911 |
gpn-1 | lon-1 | F59D12.4.1 | F48E8.1a.1 | GlyPicaN; Belongs to the glypican family. | Protein lon-1; Regulates body size morphogenesis, but does not affect male tail development; Belongs to the CRISP family. | 0.693 |
gpn-1 | lon-2 | F59D12.4.1 | C39E6.1.1 | GlyPicaN; Belongs to the glypican family. | LONg; Belongs to the glypican family. | 0.948 |
gpn-1 | sdn-1 | F59D12.4.1 | F57C7.3a.1 | GlyPicaN; Belongs to the glypican family. | Probable syndecan; Cell surface proteoglycan that bears heparan sulfate (By similarity). Required for correct mitotic spindle orientation of the ABar blastomere division plane and this may be through modulation of astral microtubule array, and in association with the wnt-signaling proteins mig-5 and dsh-2. Involved in the migration of AQR and PQR neurons, which descend from the Q neuroblasts. Promotes the axon guidance of D-type motor neurons. | 0.978 |
gpn-1 | sma-6 | F59D12.4.1 | C32D5.2.1 | GlyPicaN; Belongs to the glypican family. | Serine/threonine-protein kinase sma-6; Involved in TGF-beta pathway. May be a receptor for daf-7; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. | 0.537 |
hse-5 | gpn-1 | B0285.5.1 | F59D12.4.1 | D-glucuronyl C5-epimerase; Converts D-glucuronic acid residues adjacent to N-sulfate sugar residues to L-iduronic acids (By similarity). Plays a role in the early migration of AQR and PQR neurons, which descend from the Q neuroblasts ; Belongs to the D-glucuronyl C5-epimerase family. | GlyPicaN; Belongs to the glypican family. | 0.901 |
hse-5 | hst-2 | B0285.5.1 | C34F6.4.1 | D-glucuronyl C5-epimerase; Converts D-glucuronic acid residues adjacent to N-sulfate sugar residues to L-iduronic acids (By similarity). Plays a role in the early migration of AQR and PQR neurons, which descend from the Q neuroblasts ; Belongs to the D-glucuronyl C5-epimerase family. | Heparan sulfate 2-O-sulfotransferase hst-2; Catalyzes the transfer of sulfate to the C2-position of selected hexuronic acid residues within the maturing heparan sulfate (HS). Involved in cell adhesion and guidance by specifically modifying proteoglycans in the extracellular matrix and on the cell surface that are essential for axon migrations. | 0.956 |
hse-5 | hst-3.1 | B0285.5.1 | F40H3.5.1 | D-glucuronyl C5-epimerase; Converts D-glucuronic acid residues adjacent to N-sulfate sugar residues to L-iduronic acids (By similarity). Plays a role in the early migration of AQR and PQR neurons, which descend from the Q neuroblasts ; Belongs to the D-glucuronyl C5-epimerase family. | Sulfotransfer_1 domain-containing protein. | 0.932 |
hse-5 | hst-3.2 | B0285.5.1 | F52B10.2.1 | D-glucuronyl C5-epimerase; Converts D-glucuronic acid residues adjacent to N-sulfate sugar residues to L-iduronic acids (By similarity). Plays a role in the early migration of AQR and PQR neurons, which descend from the Q neuroblasts ; Belongs to the D-glucuronyl C5-epimerase family. | Sulfotransfer_1 domain-containing protein. | 0.927 |
hse-5 | hst-6 | B0285.5.1 | Y34B4A.3.1 | D-glucuronyl C5-epimerase; Converts D-glucuronic acid residues adjacent to N-sulfate sugar residues to L-iduronic acids (By similarity). Plays a role in the early migration of AQR and PQR neurons, which descend from the Q neuroblasts ; Belongs to the D-glucuronyl C5-epimerase family. | Heparan-sulfate 6-O-sulfotransferase; 6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparan sulfate. | 0.961 |