STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cmt-1Protein cmt-1. (238 aa)    
Predicted Functional Partners:
fzy-1
WD repeat-containing protein fzy-1; Plays a role in metaphase-anaphase transition during meiosis I. Required for embryonic anterior-posterior axis formation ; Belongs to the WD repeat CDC20/Fizzy family.
   
 
 0.866
rsy-1
Regulator of SYnapse formation.
   
   0.747
dnj-21
Mitochondrial import inner membrane translocase subunit TIM14; Probable component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. May act as a co-chaperone that stimulate the ATP-dependent activity (By similarity).
   
  
 0.574
pch-2
Putative pachytene checkpoint protein 2; Plays a key role in chromosome recombination during meiosis.
   
 
 0.553
Y56A3A.2
Peptidase_M50 domain-containing protein.
      
 0.553
psf-1
Probable DNA replication complex GINS protein PSF1; The GINS complex plays an essential role in the initiation of DNA replication.
   
    0.549
F26A1.1
Uncharacterized protein.
   
    0.542
psf-3
Sld5 domain-containing protein.
   
    0.540
sld-2
Uncharacterized protein.
   
    0.538
kbp-5
KNL (Kinetochore null) Binding Protein.
   
    0.536
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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