STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ltah-1.1Aminopeptidase ltah-1.1; Aminopeptidase which preferentially removes N-terminal Arg and Lys residues from peptides and proteins. (609 aa)    
Predicted Functional Partners:
ltah-1.2
Leuk-A4-hydro_C domain-containing protein.
  
  
0.905
gro-1
tRNA isopentenyl transferase; Belongs to the IPP transferase family.
 
    0.864
unc-101
AP-1 complex subunit mu-1-I; Component of the adaptor complexes which link clathrin to receptors in coated vesicles (Probable). Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration (Probable). Required for many aspects of development and behavior, including negative regulation of vulval differentiation. Required for the dendritic localization of potassium channel kvs-4 in the cholinergic motor neuron DA9.
      
 0.818
apm-1
MHD domain-containing protein; Belongs to the adaptor complexes medium subunit family.
      
 0.809
AC3.5
Aminopeptidase-like protein AC3.5.
  
 
 0.783
apg-1
AP-1 complex subunit gamma.
   
  
 0.703
suox-1
Cytochrome b5 heme-binding domain-containing protein.
      
 0.678
alh-13
Probable delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family.
  
  
 0.497
trxr-2
Probable glutathione reductase 2; Maintains high levels of reduced glutathione in the cytosol.
  
 0.474
trxr-1
Thioredoxin reductase 1; Together with glutathione reductase gsr-1, required for the reduction of disulfide groups in the cuticle during molting.
  
 0.472
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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