STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pnk-4Pantothenate kinase; Belongs to the type II pantothenate kinase family. (755 aa)    
Predicted Functional Partners:
F25H9.6
Flavoprotein domain-containing protein.
     
 0.998
Y71H2AM.6
Uncharacterized protein.
     
 0.994
Y65B4A.8
CTP_transf_like domain-containing protein.
    
 0.967
T05G5.5
Uncharacterized protein T05G5.5; Belongs to the CoaE family.
    
 
 0.935
F35D2.6
Uncharacterized protein.
   
  
 0.681
F31D4.2
DUF89 domain-containing protein.
      
 0.678
mxl-2
BHLH domain-containing protein.
      
 0.678
rrp-8
Ribosomal RNA-processing protein 8; Probable methyltransferase required to silence rDNA. Belongs to the methyltransferase superfamily. RRP8 family.
      
 0.678
tpk-1
Thiamin pyrophosphokinase 1; Catalyzes the phosphorylation of thiamine to thiamine pyrophosphate. Functions cell non-autonomously.
      
 0.678
bcat-1
Branched-chain-amino-acid aminotransferase, cytosolic; Catalyzes the first reaction in the catabolism of the essential branched chain amino acids leucine, isoleucine, and valine; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
      
 0.675
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.