STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
acn-1Inactive angiotensin-converting enzyme-related protein; Inactive as a metallopeptidase, due to a lack of active site residues. Required for larval molting, male tail development, and formation of adult alae. Acts in the heterochronic pathway and plays a role in the developmental timing of postembryonic hypodermal seam cell division and adult alae production. Acts synergistically with apl-1 in let-7 regulated postembryonic cell division events. Might act downstream of the heterochronic protein lin-41. Negative regulator of lifespan, heat and oxidative stress response and age-related deg [...] (906 aa)    
Predicted Functional Partners:
mlt-8
Uncharacterized protein.
   
  
 0.868
ptr-4
SSD domain-containing protein.
   
  
 0.861
mlt-11
Uncharacterized protein.
   
  
 0.859
noah-1
NOmpA Homolog (Drosophila nompA: no mechanoreceptor potential A).
   
  
 0.852
noah-2
NOmpA Homolog (Drosophila nompA: no mechanoreceptor potential A).
   
  
 0.794
mlt-9
Uncharacterized protein.
   
  
 0.715
pan-1
P-granule-associated novel protein 1; Regulates diverse developmental processes including larval molting and gonad maturation.
   
 
 0.708
lpr-5
LiPocalin-Related protein.
   
  
 0.684
bus-8
Glycosyltransferase.
   
  
 0.673
nhr-23
Nuclear hormone receptor family member nhr-23; Orphan nuclear receptor; Belongs to the nuclear hormone receptor family. NR1 subfamily.
   
  
 0.670
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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