STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dyf-7Protein dyf-7; Required for permeability of amphid and phasmid neurons to external dyes, chemotaxis to ammonium chloride, avoidance of high osmotic stimuli, male mating and dauer formation. Along with dex-1, enables neurite growth and maintenance by anchoring amphid dendritic tips during neuron cell body migration in embryonic and larval development. (446 aa)    
Predicted Functional Partners:
dex-1
Dendrite extension defective protein 1; Along with dyf-7, enables neurite growth and maintenance by anchoring amphid dendritic tips during neuron cell body migration in embryonic and larval development.
   
  
 0.963
lgc-37
Ligand-Gated ion Channel; Belongs to the ligand-gated ion channel (TC 1.A.9) family.
      
 0.808
avr-14
Uncharacterized protein; Belongs to the ligand-gated ion channel (TC 1.A.9) family.
      
 0.759
F46G11.6
ZP domain-containing protein.
   
  
 0.755
T01D1.8
ZP domain-containing protein.
   
  
 0.753
igdb-2
Ig-like and fibronectin type-III domain-containing protein 2.
      
 0.749
cut-5
ZP domain-containing protein.
   
  
 0.723
T20F5.4
Uncharacterized protein.
   
  
 0.717
frm-2
FERM domain-containing protein.
   
  
 0.712
osm-1
Intraflagellar transport protein osm-1; Component of the intraflagellar transport (IFT) complex B required for transport of proteins in the motile cilium. May be required for ciliary entrance and transport of specific ciliary cargo proteins such as che-3 which are related to motility. Required for the maintenance and formation of chemosensory cilia that detect chemosensory cues.
   
  
 0.705
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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