STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cogc-5Conserved Oligomeric Golgi (COG) Component. (656 aa)    
Predicted Functional Partners:
cogc-1
Conserved Oligomeric Golgi (COG) Component.
   
 0.994
cogc-8
Conserved oligomeric Golgi complex subunit 8; Required for normal Golgi function.
   
 0.993
cogc-6
Conserved oligomeric Golgi complex subunit 6; Required for normal Golgi function.
   
 0.992
cogc-3
Conserved Oligomeric Golgi (COG) Component.
   
 0.992
cogc-2
Conserved oligomeric Golgi complex subunit 2; Required for normal Golgi morphology and function.
   
 0.991
cogc-4
Conserved oligomeric Golgi complex subunit 4; Required for normal Golgi function; Belongs to the COG4 family.
   
 0.973
Y51H7C.41
Uncharacterized protein.
    
 
 0.867
syx-5
Putative syntaxin-5; Potentially involved in docking of synaptic vesicles at presynaptic active zones; Belongs to the syntaxin family.
   
 
 0.819
syx-16
t-SNARE coiled-coil homology domain-containing protein.
   
 
 0.764
vps-41
Vacuolar protein sorting-associated protein 41 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport pathways. Believed to act in part as a core component of the putative HOPS endosomal tethering complex which is proposed to be involved in the rab-5-to-rab-7 endosome conversion probably implicating sand-1, and via binding SNAREs and SNARE complexes to mediate tethering and docking events during SNARE-mediated membrane fusion. The HOPS complex is proposed to be recruited to rab-7 on the late endosomal membrane [...]
   
  
 0.706
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.